AutismKB 2.0

Annotation Details for FSCN1


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Basic Information Top
Gene Symbol:FSCN1 ( FLJ38511,SNL,p55 )
Gene Full Name: fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
Band: 7p22.1
Quick LinksEntrez ID:6624; OMIM: 602689; Uniprot ID:FSCN1_HUMAN; ENSEMBL ID: ENSG00000075618; HGNC ID: 11148
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IDA-stress fiber3525578
GO:0001726IDA-ruffle3525578
GO:0002102IDA-podosome20137952
GO:0005737IDA-cytoplasm9571235
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005856IDA-cytoskeleton9571235
GO:0005902IDA-microvillus9571235
GO:0005911IDA-cell-cell junction9571235
GO:0015629IDA-actin cytoskeleton3525578
GO:0030027IBA-lamellipodium-
GO:0030027ISS-lamellipodium-
GO:0030175IDA-filopodium3525578
GO:0030426IBA-growth cone-
GO:0030426ISS-growth cone-
GO:0031253IDA-cell projection membrane9571235
GO:0031941IBA-filamentous actin-
GO:0043209IEA-myelin sheath-
GO:0044393IDA-microspike3525578
GO:0070062IDA-extracellular exosome20458337
GO:0071437IDA-invadopodium20137952
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003779IDA-actin binding8999969
GO:0005515IPI-protein binding15161933
GO:0008144IDA-drug binding20393565
GO:0030674IEA-protein binding, bridging-
GO:0045296IDA-cadherin binding25468996
GO:0051015IDA-actin filament binding8999969
GO ID Evidence Qualifier GO_term References
GO:0007043IDA-cell-cell junction assembly9571235
GO:0008283TAS-cell proliferation8068206
GO:0009653IBA-anatomical structure morphogenesis-
GO:0010592IDA-positive regulation of lamellipodium assembly9571235
GO:0016477IMP-cell migration20393565
GO:0030035IDA-microspike assembly9571235
GO:0030035IMP-microspike assembly20137952
GO:0030036IDA-actin cytoskeleton organization9571235
GO:0032534IDA-regulation of microvillus assembly9571235
GO:0032956IDA-regulation of actin cytoskeleton organization20137952
GO:0035089IDA-establishment of apical/basal cell polarity9571235
GO:0048870IDA-cell motility9571235
GO:0051017IDA-actin filament bundle assembly20393565
GO:0051491IDA-positive regulation of filopodium assembly9571235
GO:0051491IMP-positive regulation of filopodium assembly20137952
GO:0071803IDA-positive regulation of podosome assembly20137952
GO:0090091IDA-positive regulation of extracellular matrix disassembly20137952
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FSCN1ACTA11065738999969 Reconstituted Complex
FSCN1ACTA11125088999969 Reconstituted Complex
FSCN1GNAS10904017353931 Affinity Capture-MS
FSCN1GNAS11250817353931 Affinity Capture-MS
FSCN1DNAJB911035416169070 Two-hybrid
FSCN1DNAJB911250816169070 Two-hybrid
FSCN1NGFR11087012789270 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FSCN1NGFR11250812789270 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FSCN1PRKCA11250814532112 Affinity Capture-Western; Reconstituted Complex
FSCN1PRKCA11156414532112 Affinity Capture-Western; Reconstituted Complex
FSCN1RAB1A11250816169070 Two-hybrid
FSCN1RAB1A11179916169070 Two-hybrid
VHLFSCN111250817353931 Affinity Capture-MS
VHLFSCN111326917353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352745
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031009-1'