AutismKB 2.0

Annotation Details for SNX2


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Basic Information Top
Gene Symbol:SNX2 ( MGC5204,TRG-9 )
Gene Full Name: sorting nexin 2
Band: 5q23.2
Quick LinksEntrez ID:6643; OMIM: 605929; Uniprot ID:SNX2_HUMAN; ENSEMBL ID: ENSG00000205302; HGNC ID: 11173
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11279102
GO:0005764IDA-lysosome-
GO:0005768IDA-endosome-
GO:0005829IEA-cytosol-
GO:0010008IDA-endosome membrane15673616
GO:0016020IDA-membrane9819414
GO:0019898IBA-extrinsic component of membrane-
GO:0030027IEA-lamellipodium-
GO:0030904IDA-retromer complex11102511
GO:0030905IPI-retromer, tubulation complex11102511
GO:0030905NAS-retromer, tubulation complex26220253
GO:0031901IEA-early endosome membrane-
GO:0043234IDA-protein complex9819414
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005154IDA-epidermal growth factor receptor binding9819414
GO:0005158IDA-insulin receptor binding9819414
GO:0005515IPI-protein binding11278302
GO:0035091IBA-phosphatidylinositol binding-
GO:0042803IPI-protein homodimerization activity11102511
GO:0045296IDA-cadherin binding25468996
GO:0046982IPI-protein heterodimerization activity11102511
GO:0046982NAS-protein heterodimerization activity26220253
GO:1990459IDA-transferrin receptor binding9819414
GO:1990460IDA-leptin receptor binding9819414
GO ID Evidence Qualifier GO_term References
GO:0006886IEA-intracellular protein transport-
GO:0006897IBA-endocytosis-
GO:0016050IBA-vesicle organization-
GO:0034498IBA-early endosome to Golgi transport-
GO:0042147IMP-retrograde transport, endosome to Golgi20138391
GO:0042147NAS-retrograde transport, endosome to Golgi26220253
GO:0051259IDA-protein oligomerization9819414
GO:0072673IDA-lamellipodium morphogenesis20604901
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SNX2ACVR1B11252611279102 Affinity Capture-Western
SNX2ACVR1B10660611279102 Affinity Capture-Western
SNX2ACVR2B11252611279102 Affinity Capture-Western
SNX2ACVR2B10660811279102 Affinity Capture-Western
SNX2EGFR1125269819414 Affinity Capture-Western
SNX2EGFR1082769819414 Affinity Capture-Western
SNX2INSR1125269819414 Affinity Capture-Western
SNX2INSR1098549819414 Affinity Capture-Western
SNX2LEPR1125269819414 Affinity Capture-Western
SNX2LEPR1101449819414 Affinity Capture-Western
SNX2PDGFRA1125269819414 Affinity Capture-Western
SNX2PDGFRA1111829819414 Affinity Capture-Western
SNX2PDGFRB1111859819414 Affinity Capture-Western
SNX2PDGFRB1125269819414 Affinity Capture-Western
SNX2SNX11125259819414 Affinity Capture-Western
SNX2SNX11125269819414 Affinity Capture-Western
SNX4SNX21125269819414 Affinity Capture-Western
SNX4SNX21142629819414 Affinity Capture-Western
SNX6SNX211252611279102 Affinity Capture-Western
SNX6SNX212185211279102 Affinity Capture-Western
FNBP1SNX211252611438682 14596906 Affinity Capture-Western; Two-hybrid
FNBP1SNX211668611438682 14596906 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1915054
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051120-45'