AutismKB 2.0

Annotation Details for SOD2


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Basic Information Top
Gene Symbol:SOD2 ( IPOB,MNSOD,MVCD6 )
Gene Full Name: superoxide dismutase 2, mitochondrial
Band: 6q25.3
Quick LinksEntrez ID:6648; OMIM: 147460; Uniprot ID:SODM_HUMAN; ENSEMBL ID: ENSG00000112096; HGNC ID: 11180
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion12551919
GO:0005759TAS-mitochondrial matrix10511315
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004784IDA-superoxide dismutase activity12551919
GO:0004784TAS-superoxide dismutase activity-
GO:0030145IDA-manganese ion binding19265433
GO:0030145TAS-manganese ion binding10511315
GO:0042802IPI-identical protein binding19822147
GO ID Evidence Qualifier GO_term References
GO:0000303IMP-response to superoxide16179351
GO:0001315IMP-age-dependent response to reactive oxygen species14980699
GO:0001836ISS-release of cytochrome c from mitochondria-
GO:0003069ISS-acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure-
GO:0006357IMP-regulation of transcription from RNA polymerase II promoter9393747
GO:0006801IDA-superoxide metabolic process12551919
GO:0007005TAS-mitochondrion organization-
GO:0008217ISS-regulation of blood pressure-
GO:0008285IMP-negative regulation of cell proliferation16179351
GO:0019430IMP-removal of superoxide radicals16179351
GO:0030335IMP-positive regulation of cell migration20489163
GO:0032364IMP-oxygen homeostasis16179351
GO:0034599TAS-cellular response to oxidative stress-
GO:0043524IGI-negative regulation of neuron apoptotic process17251466
GO:0051289IPI-protein homotetramerization19265433
GO:0055114IEA-oxidation-reduction process-
GO:1902176IMP-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway12551919
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SOD2RPS3A11253116169070 Two-hybrid
SOD2RPS3A11210316169070 Two-hybrid
NOL12SOD211253116169070 Two-hybrid
NOL12SOD212257716169070 Two-hybrid
AURKASOD211253117353931 Affinity Capture-MS
AURKASOD211266617353931 Affinity Capture-MS
SUMO1SOD211253117549794 Affinity Capture-MS
SUMO1SOD211318817549794 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
SOD2rs1799725, rs2758346, rs2855116, rs4880, rs5746136 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
SOD2rs4880 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
SOD2rs2758331, rs4880, rs5746105 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:98352
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7742'