AutismKB 2.0

Annotation Details for SOX10


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Basic Information Top
Gene Symbol:SOX10 ( DOM,MGC15649,PCWH,WS2E,WS4,WS4C )
Gene Full Name: SRY (sex determining region Y)-box 10
Band: 22q13.1
Quick LinksEntrez ID:6663; OMIM: 602229; Uniprot ID:SOX10_HUMAN; ENSEMBL ID: ENSG00000100146; HGNC ID: 11190
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18512230
GO:0005634ISS-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0031315IEA-extrinsic component of mitochondrial outer membrane-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000980IEA-RNA polymerase II distal enhancer sequence-specific DNA binding-
GO:0001190IEA-transcriptional activator activity, RNA polymerase II transcription factor binding-
GO:0003682IEA-chromatin binding-
GO:0003705IEA-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0003713TAS-transcription coactivator activity9722528
GO:0005515IPI-protein binding11029584
GO:0008134IEA-transcription factor binding-
GO:0042802IPI-identical protein binding11029584
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0001755IEA-neural crest cell migration-
GO:0002052IEA-positive regulation of neuroblast proliferation-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9722528
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007422IEA-peripheral nervous system development-
GO:0009653TAS-anatomical structure morphogenesis9425902
GO:0014015IEA-positive regulation of gliogenesis-
GO:0030318IEA-melanocyte differentiation-
GO:0032808IEA-lacrimal gland development-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045892IEA-negative regulation of transcription, DNA-templated-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0048469IEA-cell maturation-
GO:0048484IEA-enteric nervous system development-
GO:0048546IEA-digestive tract morphogenesis-
GO:0048589IEA-developmental growth-
GO:0048709IEA-oligodendrocyte differentiation-
GO:0061138IEA-morphogenesis of a branching epithelium-
GO:0090090IEA-negative regulation of canonical Wnt signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SOX10PAX311254610942418 12668617 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SOX10PAX311111110942418 12668617 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
SOX10PAX318535011029584 Pax3 interacts with Sox10.
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SOX10SOX10_02, SOX10_03, rs139883, rs139884, rs139885, rs139887, rs139888 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:98358
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-011207-1'