AutismKB 2.0

Annotation Details for SPN


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Basic Information Top
Gene Symbol:SPN ( CD43,GPL115,LSN )
Gene Full Name: sialophorin
Band: 16p11.2
Quick LinksEntrez ID:6693; OMIM: 182160; Uniprot ID:LEUK_HUMAN; ENSEMBL ID: ENSG00000197471; HGNC ID: 11249
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001931IEA-uropod-
GO:0005604IEA-basement membrane-
GO:0005615IDA-extracellular space10899905
GO:0005886TAS-plasma membrane-
GO:0005887IEA-integral component of plasma membrane-
GO:0009897IEA-external side of plasma membrane-
GO:0009986IDA-cell surface20605918
GO:0016020IDA-membrane19946888
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0004888TAS-transmembrane signaling receptor activity1683685
GO:0030544IPI-Hsp70 protein binding20633027
GO:0031072IPI-heat shock protein binding20633027
GO ID Evidence Qualifier GO_term References
GO:0001562IEA-response to protozoan-
GO:0001808IEA-negative regulation of type IV hypersensitivity-
GO:0001934IEA-positive regulation of protein phosphorylation-
GO:0006935TAS-chemotaxis10753822
GO:0006955TAS-immune response2023632
GO:0006968TAS-cellular defense response1683685
GO:0007162TAS-negative regulation of cell adhesion10753822
GO:0007163TAS-establishment or maintenance of cell polarity10753822
GO:0007165TAS-signal transduction2023632
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0031295IEA-T cell costimulation-
GO:0042102IEA-positive regulation of T cell proliferation-
GO:0042130IEA-negative regulation of T cell proliferation-
GO:0042535IDA-positive regulation of tumor necrosis factor biosynthetic process10899905
GO:0042742IDA-defense response to bacterium10899905
GO:0045060IEA-negative thymic T cell selection-
GO:0050688IEA-regulation of defense response to virus-
GO:0050900TAS-leukocyte migration-
GO:0097190IEA-apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SPNLGALS111257110490978 Affinity Capture-Western
SPNLGALS111014710490978 Affinity Capture-Western
SPNMSN1125719472040 9616160 Affinity Capture-Western; Reconstituted Complex
SPNMSN1105849472040 9616160 Affinity Capture-Western; Reconstituted Complex
EZRSPN1125719616160 Affinity Capture-Western; Reconstituted Complex
EZRSPN1132719616160 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98384
  • Data Attributes: MGI curated and HomoloGene calculated