AutismKB 2.0

Annotation Details for SPP2


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Basic Information Top
Gene Symbol:SPP2 ( SPP24 )
Gene Full Name: secreted phosphoprotein 2, 24kDa
Band: 2q37.1
Quick LinksEntrez ID:6694; OMIM: 602637; Uniprot ID:SPP24_HUMAN; ENSEMBL ID: ENSG00000072080; HGNC ID: 11256
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0031089TAS-platelet dense granule lumen-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004866TAS-endopeptidase inhibitor activity7814406
GO ID Evidence Qualifier GO_term References
GO:0001501TAS-skeletal system development7814406
GO:0002576TAS-platelet degranulation-
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
GO:0046849IEA-bone remodeling-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1922646
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018