AutismKB 2.0

Annotation Details for SPR


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Basic Information Top
Gene Symbol:SPR ( SDR38C1 )
Gene Full Name: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Band: 2p13.2
Quick LinksEntrez ID:6697; OMIM: 182125; Uniprot ID:SPRE_HUMAN; ENSEMBL ID: ENSG00000116096; HGNC ID: 11257
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004033TAS-aldo-keto reductase (NADP) activity1883349
GO:0004757ISS-sepiapterin reductase activity-
GO:0004757TAS-sepiapterin reductase activity-
GO:0050661TAS-NADP binding1883349
GO ID Evidence Qualifier GO_term References
GO:0006729TAS-tetrahydrobiopterin biosynthetic process1883349
GO:0006809IDA-nitric oxide biosynthetic process15197144
GO:0050999TAS-regulation of nitric-oxide synthase activity-
GO:0055114TAS-oxidation-reduction process1883349
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
SPRD2S1394, D2S145, D2S2109, D2S2110, D2S2111, rs1150500, rs1161265, rs1161267, rs1396107, rs1508060, rs1561244, rs1561245, rs1567229, rs1567230, rs1876487, rs1876488, rs1876491, rs2048170, rs2135985, rs2421095, rs4852902, rs4852903, rs6730083 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:103078
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050522-412'