AutismKB 2.0

Annotation Details for SPTB


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Basic Information Top
Gene Symbol:SPTB ( EL3,HS2,HSPTB1,SPH2 )
Gene Full Name: spectrin, beta, erythrocytic
Band: 14q23.3
Quick LinksEntrez ID:6710; OMIM: 182870; Uniprot ID:SPTB1_HUMAN; ENSEMBL ID: ENSG00000070182; HGNC ID: 11274
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IDA-Golgi apparatus-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0008091IEA-spectrin-
GO:0014731IDA-spectrin-associated cytoskeleton379653
GO:0015629TAS-actin cytoskeleton10950304
GO:0031235TAS-intrinsic component of the cytoplasmic side of the plasma membrane10950304
GO:0043234IDA-protein complex16060676
GO ID Evidence Qualifier GO_term References
GO:0003779TAS-actin binding2195026
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005200IEA-structural constituent of cytoskeleton-
GO:0005515IPI-protein binding10751147
GO:0030506IPI-ankyrin binding8159688
GO:0051015IDA-actin filament binding16060676
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0006888TAS-ER to Golgi vesicle-mediated transport-
GO:0007010IEA-cytoskeleton organization-
GO:0007411TAS-axon guidance-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051693IEA-actin filament capping-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SPTBADD11066318663089 Reconstituted Complex
SPTBADD11125888663089 Reconstituted Complex
SPTBANK11125882141335 15929114 Biochemical Activity; Reconstituted Complex
SPTBANK11067832141335 15929114 Biochemical Activity; Reconstituted Complex
SPTBEPB411083497673158 Reconstituted Complex
SPTBEPB411125887673158 Reconstituted Complex
SPTBSPTA11125861634521 Protein-peptide
SPTBSPTA11125881634521 Protein-peptide
SPTBSPTAN11125879890967 Reconstituted Complex
SPTBSPTAN11125889890967 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98387
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000906-1'