AutismKB 2.0

Annotation Details for SPTBN2


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Basic Information Top
Gene Symbol:SPTBN2 ( GTRAP41,SCA5 )
Gene Full Name: spectrin, beta, non-erythrocytic 2
Band: 11q13.2
Quick LinksEntrez ID:6712; OMIM: 604985; Uniprot ID:SPTN2_HUMAN; ENSEMBL ID: ENSG00000173898; HGNC ID: 11276
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space22664934
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0008091IDA-spectrin9826670
GO:0016324IEA-apical plasma membrane-
GO:0030054IDA-cell junction-
GO:0043025IEA-neuronal cell body-
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005200TAS-structural constituent of cytoskeleton9826670
GO:0005543IEA-phospholipid binding-
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0006888TAS-ER to Golgi vesicle-mediated transport-
GO:0007010IEA-cytoskeleton organization-
GO:0007411TAS-axon guidance-
GO:0007416IEA-synapse assembly-
GO:0016192IDA-vesicle-mediated transport9826670
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0021692IEA-cerebellar Purkinje cell layer morphogenesis-
GO:0030534IEA-adult behavior-
GO:0035264IEA-multicellular organism growth-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051693IEA-actin filament capping-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SPTBN2ACTB10657511357136 11461920 Reconstituted Complex
SPTBN2ACTB11259011357136 11461920 Reconstituted Complex
SPTBN2APC11259020936779 Two-hybrid
SPTBN2APC10682120936779 Two-hybrid
UNC13BSPTBN21157599704016 Reconstituted Complex; Two-hybrid
UNC13BSPTBN21125909704016 Reconstituted Complex; Two-hybrid
ACTR1ASPTBN211259011357136 11461920 Reconstituted Complex; Two-hybrid
ACTR1ASPTBN211542511357136 11461920 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1313261
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-787'