AutismKB 2.0

Annotation Details for SRPK2


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Basic Information Top
Gene Symbol:SRPK2 ( FLJ36101,SFRSK2 )
Gene Full Name: SRSF protein kinase 2
Band: 7q22.3
Quick LinksEntrez ID:6733; OMIM: 602980; Uniprot ID:SRPK2_HUMAN; ENSEMBL ID: ENSG00000135250; HGNC ID: 11306
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus9472028
GO:0005654IDA-nucleoplasm-
GO:0005730IDA-nucleolus-
GO:0005737IDA-cytoplasm9472028
GO:0005829IDA-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding9472028
GO:0003723IDA-RNA binding22658674
GO:0004674IDA-protein serine/threonine kinase activity9472028
GO:0005515IPI-protein binding16189514
GO:0005524IDA-ATP binding9472028
GO:0071889ISS-14-3-3 protein binding-
GO ID Evidence Qualifier GO_term References
GO:0000245IDA-spliceosomal complex assembly9472028
GO:0001525ISS-angiogenesis-
GO:0006468IDA-protein phosphorylation9472028
GO:0008284IDA-positive regulation of cell proliferation18559500
GO:0008380IDA-RNA splicing9472028
GO:0010628ISS-positive regulation of gene expression-
GO:0030154IEA-cell differentiation-
GO:0035063ISS-nuclear speck organization-
GO:0035556IDA-intracellular signal transduction9472028
GO:0043525ISS-positive regulation of neuron apoptotic process-
GO:0045070IDA-positive regulation of viral genome replication20498328
GO:0045071IDA-negative regulation of viral genome replication12417631
GO:0045087IC-innate immune response12417631
GO:0045787ISS-positive regulation of cell cycle-
GO:0048024TAS-regulation of mRNA splicing, via spliceosome21205200
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SRPK2SRSF11126119472028 10196197 12565863 Affinity Capture-Western; Biochemical Activity
SRPK2SRSF11123249472028 10196197 12565863 Affinity Capture-Western; Biochemical Activity
SRPK2SRSF21126119472028 Biochemical Activity
SRPK2SRSF21123259472028 Biochemical Activity
SRPK2SRSF31123269472028 Biochemical Activity
SRPK2SRSF31126119472028 Biochemical Activity
SRPK2SRSF51123289472028 Biochemical Activity
SRPK2SRSF51126119472028 Biochemical Activity
SRPK2SRSF61123299472028 Biochemical Activity
SRPK2SRSF61126119472028 Biochemical Activity
SRPK2SNRNP701125099472028 Biochemical Activity
SRPK2SNRNP701126119472028 Biochemical Activity
U2AF2SRPK21126119472028 16189514 Biochemical Activity; Two-hybrid
U2AF2SRPK21164669472028 16189514 Biochemical Activity; Two-hybrid
LUC7L3SRPK211971012565863 Biochemical Activity
LUC7L3SRPK211261112565863 Biochemical Activity
RNPS1SRPK211612517353931 Affinity Capture-MS
RNPS1SRPK211261117353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1201408
  • Data Attributes: MGI curated and HomoloGene calculated
No data