AutismKB 2.0

Annotation Details for SSTR2


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Basic Information Top
Gene Symbol:SSTR2 ( - )
Gene Full Name: somatostatin receptor 2
Band: 17q25.1
Quick LinksEntrez ID:6752; OMIM: 182452; Uniprot ID:SSR2_HUMAN; ENSEMBL ID: ENSG00000180616; HGNC ID: 11331
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7914078
GO:0043005IBA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0004994IBA-somatostatin receptor activity-
GO:0005515IPI-protein binding10551867
GO:0030165IPI-PDZ domain binding10551867
GO:0042923IBA-neuropeptide binding-
GO ID Evidence Qualifier GO_term References
GO:0006937IEA-regulation of muscle contraction-
GO:0007187TAS-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger7914078
GO:0007193IEA-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-
GO:0007218IEA-neuropeptide signaling pathway-
GO:0007267TAS-cell-cell signaling1346068
GO:0007283IEA-spermatogenesis-
GO:0007584TAS-response to nutrient1346068
GO:0007586TAS-digestion1346068
GO:0008285TAS-negative regulation of cell proliferation9892014
GO:0021549IEA-cerebellum development-
GO:0030432IEA-peristalsis-
GO:0030900IEA-forebrain development-
GO:0038170IEA-somatostatin signaling pathway-
GO:0042594IEA-response to starvation-
GO:0071385IBA-cellular response to glucocorticoid stimulus-
GO:0071392IBA-cellular response to estradiol stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SSTR2CORT1077189125122 Protein-peptide
SSTR2CORT1126309125122 Protein-peptide
SSTR2PTPN61117429305905 Affinity Capture-Western
SSTR2PTPN61126309305905 Affinity Capture-Western
SHANK1SSTR211917110551867 Affinity Capture-Western; Reconstituted Complex
SHANK1SSTR211263010551867 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98328
  • Data Attributes: MGI curated and HomoloGene calculated
No data