AutismKB 2.0

Annotation Details for ZFP36L1


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Basic Information Top
Gene Symbol:ZFP36L1 ( BRF1,Berg36,ERF-1,ERF1,RNF162B,TIS11B,cMG1 )
Gene Full Name: zinc finger protein 36, C3H type-like 1
Band: 14q24.1
Quick LinksEntrez ID:677; OMIM: 601064; Uniprot ID:TISB_HUMAN; ENSEMBL ID: ENSG00000185650; HGNC ID: 1107
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000932IDA-P-body17369404
GO:0005634IDA-nucleus12198173
GO:0005737IDA-cytoplasm12198173
GO:0005829IBA-cytosol-
GO:0005829TAS-cytosol-
GO:0030529IDA-intracellular ribonucleoprotein complex15687258
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding8595910
GO:0003723IDA-RNA binding22658674
GO:0003729IDA-mRNA binding15467755
GO:0005515IPI-protein binding15687258
GO:0035925IDA-mRNA 3'-UTR AU-rich region binding12198173
GO:0046872IEA-metal ion binding-
GO:0071889IDA-14-3-3 protein binding15538381
GO ID Evidence Qualifier GO_term References
GO:0000165IDA-MAPK cascade18326031
GO:0000288IEA-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-
GO:0001570IEA-vasculogenesis-
GO:0003342IEA-proepicardium development-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006397IEA-mRNA processing-
GO:0006915IEA-apoptotic process-
GO:0007507IEA-heart development-
GO:0008283IEA-cell proliferation-
GO:0009611IDA-response to wounding27182009
GO:0010468IDA-regulation of gene expression20166898
GO:0010837IMP-regulation of keratinocyte proliferation27182009
GO:0014065IDA-phosphatidylinositol 3-kinase signaling15538381
GO:0021915IEA-neural tube development-
GO:0031086ISS-nuclear-transcribed mRNA catabolic process, deadenylation-independent decay-
GO:0031440IDA-regulation of mRNA 3'-end processing21832157
GO:0032869IDA-cellular response to insulin stimulus15538381
GO:0033077ISS-T cell differentiation in thymus-
GO:0035264IEA-multicellular organism growth-
GO:0038066ISS-p38MAPK cascade-
GO:0043488IDA-regulation of mRNA stability15467755
GO:0043488IMP-regulation of mRNA stability12198173
GO:0043488TAS-regulation of mRNA stability-
GO:0043491ISS-protein kinase B signaling-
GO:0044344ISS-cellular response to fibroblast growth factor stimulus-
GO:0045577ISS-regulation of B cell differentiation-
GO:0045600ISS-positive regulation of fat cell differentiation-
GO:0045616IMP-regulation of keratinocyte differentiation27182009
GO:0045647IDA-negative regulation of erythrocyte differentiation20702587
GO:0045657IDA-positive regulation of monocyte differentiation26542173
GO:0045661ISS-regulation of myoblast differentiation-
GO:0048382ISS-mesendoderm development-
GO:0051028IMP-mRNA transport17369404
GO:0060710IEA-chorio-allantoic fusion-
GO:0060712IEA-spongiotrophoblast layer development-
GO:0061158IDA-3'-UTR-mediated mRNA destabilization15467755
GO:0061158IMP-3'-UTR-mediated mRNA destabilization12198173
GO:0070371IDA-ERK1 and ERK2 cascade25106868
GO:0071320IDA-cellular response to cAMP19179481
GO:0071356IDA-cellular response to tumor necrosis factor20166898
GO:0071364IDA-cellular response to epidermal growth factor stimulus20166898
GO:0071375IDA-cellular response to peptide hormone stimulus15467755
GO:0071385IDA-cellular response to glucocorticoid stimulus20166898
GO:0071456IMP-cellular response to hypoxia21832157
GO:0071472ISS-cellular response to salt stress-
GO:0071560IDA-cellular response to transforming growth factor beta stimulus20166898
GO:0072091ISS-regulation of stem cell proliferation-
GO:0097403ISS-cellular response to raffinose-
GO:1900153ISS-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-
GO:1901991ISS-negative regulation of mitotic cell cycle phase transition-
GO:1902172IMP-regulation of keratinocyte apoptotic process27182009
GO:1904582IMP-positive regulation of intracellular mRNA localization17369404
GO:1904628IDA-cellular response to phorbol 13-acetate 12-myristate25106868
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PAFAH1B2ZFP36L110714416169070 Two-hybrid
PAFAH1B2ZFP36L111108616169070 Two-hybrid
MAPK14ZFP36L110781916189514 Affinity Capture-Western; Two-hybrid
MAPK14ZFP36L110714416189514 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107946
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2391'