AutismKB 2.0

Annotation Details for STAT2


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Basic Information Top
Gene Symbol:STAT2 ( ISGF-3,MGC59816,P113,STAT113 )
Gene Full Name: signal transducer and activator of transcription 2, 113kDa
Band: 12q13.2
Quick LinksEntrez ID:6773; OMIM: 600556; Uniprot ID:STAT2_HUMAN; ENSEMBL ID: ENSG00000170581; HGNC ID: 11363
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0004871IEA-signal transducer activity-
GO:0005515IPI-protein binding8605876
GO:0042802IPI-identical protein binding8605877
GO ID Evidence Qualifier GO_term References
GO:0001932IMP-regulation of protein phosphorylation26122121
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9020188
GO:0007259TAS-JAK-STAT cascade9020188
GO:0051607IMP-defense response to virus23391734
GO:0060337IMP-type I interferon signaling pathway23391734
GO:0060337TAS-type I interferon signaling pathway-
GO:0060338TAS-regulation of type I interferon-mediated signaling pathway-
GO:0090140IMP-regulation of mitochondrial fission26122121
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STAT2CREBBP1126508848048 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT2CREBBP1077778848048 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT2EP30011265010464260 15154850 Reconstituted Complex
STAT2EP30010834710464260 15154850 Reconstituted Complex
STAT2IFNAR11126507559568 8605876 9121453 Affinity Capture-Western; Reconstituted Complex
STAT2IFNAR11096767559568 8605876 9121453 Affinity Capture-Western; Reconstituted Complex
STAT2IFNAR21126509121453 11786546 Affinity Capture-Western; Reconstituted Complex
STAT2IFNAR21096779121453 11786546 Affinity Capture-Western; Reconstituted Complex
STAT2SMARCA411265012244326 Affinity Capture-Western; Reconstituted Complex
STAT2SMARCA411248112244326 Affinity Capture-Western; Reconstituted Complex
STAT2SMARCC111265012244326 Affinity Capture-Western
STAT2SMARCC111248312244326 Affinity Capture-Western
STAT2SMARCC211265012244326 Affinity Capture-Western
STAT2SMARCC211248512244326 Affinity Capture-Western
STAT2SMARCE111265012244326 Affinity Capture-Western
STAT2SMARCE111248912244326 Affinity Capture-Western
STAT2STAT11126498621447 10446176 12048190 Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex
STAT2STAT11126508621447 10446176 12048190 Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex
IRF9STAT21126508943351 9242679 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IRF9STAT21156528943351 9242679 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MED14STAT211265012509459 Affinity Capture-Western; Reconstituted Complex
MED14STAT211469912509459 Affinity Capture-Western; Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
STAT2STAT118261515467722 STAT1 interacts with STAT2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103039
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080321-1'