AutismKB 2.0

Annotation Details for STAT5A


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Basic Information Top
Gene Symbol:STAT5A ( MGF,STAT5 )
Gene Full Name: signal transducer and activator of transcription 5A
Band: 17q21.2
Quick LinksEntrez ID:6776; OMIM: 601511; Uniprot ID:STA5A_HUMAN; ENSEMBL ID: ENSG00000126561; HGNC ID: 11366
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0004713TAS-protein tyrosine kinase activity-
GO:0004871IEA-signal transducer activity-
GO:0005515IPI-protein binding12237455
GO ID Evidence Qualifier GO_term References
GO:0000255ISS-allantoin metabolic process-
GO:0001938IMP-positive regulation of endothelial cell proliferation20489169
GO:0006101ISS-citrate metabolic process-
GO:0006103ISS-2-oxoglutarate metabolic process-
GO:0006105ISS-succinate metabolic process-
GO:0006107ISS-oxaloacetate metabolic process-
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter8631883
GO:0006549ISS-isoleucine metabolic process-
GO:0006573ISS-valine metabolic process-
GO:0006600ISS-creatine metabolic process-
GO:0006631ISS-fatty acid metabolic process-
GO:0007259TAS-JAK-STAT cascade7719937
GO:0007595IEA-lactation-
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0019530ISS-taurine metabolic process-
GO:0038161ISS-prolactin signaling pathway-
GO:0040014ISS-regulation of multicellular organism growth-
GO:0043536IMP-positive regulation of blood vessel endothelial cell migration20489169
GO:0046449ISS-creatinine metabolic process-
GO:0060397TAS-JAK-STAT cascade involved in growth hormone signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STAT5ABRCA111265312459499 Affinity Capture-Western
STAT5ABRCA110714012459499 Affinity Capture-Western
STAT5ABRCA210714212459499 Affinity Capture-Western
STAT5ABRCA211265312459499 Affinity Capture-Western
STAT5ACD2471073579880255 Affinity Capture-Western
STAT5ACD2471126539880255 Affinity Capture-Western
STAT5ACRKL1077899837784 Affinity Capture-Western; Reconstituted Complex
STAT5ACRKL1126539837784 Affinity Capture-Western; Reconstituted Complex
STAT5AEGFR11265310358079 16729043 Affinity Capture-MS; Affinity Capture-Western
STAT5AEGFR10827610358079 16729043 Affinity Capture-MS; Affinity Capture-Western
STAT5AEPOR1126538977232 15644415 Affinity Capture-Western; PCA; Reconstituted Complex
STAT5AEPOR1083718977232 15644415 Affinity Capture-Western; PCA; Reconstituted Complex
STAT5AERBB411265315534001 16729043 Affinity Capture-MS; Affinity Capture-Western
STAT5AERBB410837815534001 16729043 Affinity Capture-MS; Affinity Capture-Western
STAT5AESR111265311682624 Reconstituted Complex
STAT5AESR110840311682624 Reconstituted Complex
STAT5AESR211265311682624 Reconstituted Complex
STAT5AESR210840411682624 Reconstituted Complex
STAT5AFGFR211265321464042 Affinity Capture-Western
STAT5AFGFR210855421464042 Affinity Capture-Western
STAT5AHDAC111265312574125 Affinity Capture-Western
STAT5AHDAC110931512574125 Affinity Capture-Western
STAT5APRMT111265318413343 Affinity Capture-Western; Reconstituted Complex
STAT5APRMT110951218413343 Affinity Capture-Western; Reconstituted Complex
STAT5AIL2RB11265310602027 Reconstituted Complex
STAT5AIL2RB10977510602027 Reconstituted Complex
STAT5AJAK11126539047382 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT5AJAK11099199047382 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT5AJAK21126539047382 9575217 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT5AJAK21099209047382 9575217 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT5AJAK31099219047382 18250158 Affinity Capture-Western; Two-hybrid
STAT5AJAK31126539047382 18250158 Affinity Capture-Western; Two-hybrid
STAT5AMAGEA1211265316189514 Two-hybrid
STAT5AMAGEA1211028516189514 Two-hybrid
STAT5APGR11265321464042 Affinity Capture-Western
STAT5APGR11126021464042 Affinity Capture-Western
STAT5AMAPK111265310194762 10996427 Affinity Capture-Western; Reconstituted Complex
STAT5AMAPK111158010194762 10996427 Affinity Capture-Western; Reconstituted Complex
STAT5APTPN111265312237455 Protein-peptide
STAT5APTPN111173612237455 Protein-peptide
STAT5APTPN1111265310617656 12060651 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
STAT5APTPN1111174510617656 12060651 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
STAT5ASHC111236110996427 Affinity Capture-Western
STAT5ASHC111265310996427 Affinity Capture-Western
STAT5ASMARCA411265317387179 Affinity Capture-Western
STAT5ASMARCA411248117387179 Affinity Capture-Western
NMISTAT5A1126539989503 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NMISTAT5A1145619989503 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA1STAT5A11420012954634 Affinity Capture-Western
NCOA1STAT5A11265312954634 Affinity Capture-Western
PRTFDC1STAT5A11265316189514 Two-hybrid
PRTFDC1STAT5A12127616189514 Two-hybrid
CARM1STAT5A11265318413343 Affinity Capture-Western; Reconstituted Complex
CARM1STAT5A11576018413343 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103036
  • Data Attributes: MGI curated and HomoloGene calculated
No data