AutismKB 2.0

Annotation Details for STXBP3


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Basic Information Top
Gene Symbol:STXBP3 ( MUNC18-3,MUNC18C,PSP,UNC-18C )
Gene Full Name: syntaxin binding protein 3
Band: 1p13.3
Quick LinksEntrez ID:6814; OMIM: 608339; Uniprot ID:STXB3_HUMAN; ENSEMBL ID: ENSG00000116266; HGNC ID: 11446
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol18588921
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane18588921
GO:0016323IEA-basolateral plasma membrane-
GO:0016324IEA-apical plasma membrane-
GO:0031091IDA-platelet alpha granule12773094
GO:0042581IDA-specific granule18588921
GO:0070062IDA-extracellular exosome20458337
GO:0070820IDA-tertiary granule18588921
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12773094
GO:0017075IEA-syntaxin-1 binding-
GO:0019905IPI-syntaxin binding12773094
GO ID Evidence Qualifier GO_term References
GO:0006904IEA-vesicle docking involved in exocytosis-
GO:0007420IEA-brain development-
GO:0015758IEA-glucose transport-
GO:0022615IEA-protein to membrane docking-
GO:0030073IEA-insulin secretion-
GO:0032868IEA-response to insulin-
GO:0043312IEP-neutrophil degranulation18588921
GO:0045955IMP-negative regulation of calcium ion-dependent exocytosis12649283
GO:0051291IEA-protein heterooligomerization-
GO:0070527IMP-platelet aggregation12773094
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STXBP3STX210836812773094 Affinity Capture-Western
STXBP3STX211268312773094 Affinity Capture-Western
STXBP3STX411267912773094 12832401 Affinity Capture-Western; Two-hybrid
STXBP3STX411268312773094 12832401 Affinity Capture-Western; Two-hybrid
SNAP23STXBP311430312773094 Affinity Capture-Western
SNAP23STXBP311268312773094 Affinity Capture-Western
SNTG1STXBP311992812832401 Reconstituted Complex
SNTG1STXBP311268312832401 Reconstituted Complex
VAMP2STXBP311268312832401 Reconstituted Complex
VAMP2STXBP311271112832401 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107362
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2833'