AutismKB 2.0

Annotation Details for SUPT6H


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Basic Information Top
Gene Symbol:SUPT6H ( KIAA0162,MGC87943,SPT6,SPT6H,emb-5 )
Gene Full Name: suppressor of Ty 6 homolog (S. cerevisiae)
Band: 17q11.2
Quick LinksEntrez ID:6830; OMIM: 601333; Uniprot ID:SPT6H_HUMAN; ENSEMBL ID: ENSG00000109111; HGNC ID: 11470
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634NAS-nucleus8786132
GO:0005654TAS-nucleoplasm-
GO:0008023IBA-transcription elongation factor complex-
GO:0035327IBA-transcriptionally active chromatin-
GO ID Evidence Qualifier GO_term References
GO:0000991IBA-transcription factor activity, core RNA polymerase II binding-
GO:0003677IEA-DNA binding-
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding8786132
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding10933715
GO:0031491IBA-nucleosome binding-
GO:0042393IDA-histone binding10933715
GO ID Evidence Qualifier GO_term References
GO:0006338NAS-chromatin remodeling8786132
GO:0006342IBA-chromatin silencing-
GO:0006355NAS-regulation of transcription, DNA-templated8786132
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0006397IEA-mRNA processing-
GO:0008380IEA-RNA splicing-
GO:0010793ISS-regulation of mRNA export from nucleus-
GO:0016032IEA-viral process-
GO:0032968IMP-positive regulation of transcription elongation from RNA polymerase II promoter17234882
GO:0034728IBA-nucleosome organization-
GO:0042789IBA-mRNA transcription from RNA polymerase II promoter-
GO:0045191ISS-regulation of isotype switching-
GO:0050684IBA-regulation of mRNA processing-
GO:0050684ISS-regulation of mRNA processing-
GO:0051028IEA-mRNA transport-
GO:0051147ISS-regulation of muscle cell differentiation-
GO:0061086IMP-negative regulation of histone H3-K27 methylation23503590
GO:0070827IBA-chromatin maintenance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SUPT6HPOLR2A11269819141475 Far Western
SUPT6HPOLR2A11142619141475 Far Western
TCEA1SUPT6H11269817643375 Affinity Capture-MS
TCEA1SUPT6H11277917643375 Affinity Capture-MS
IWS1SUPT6H11269819141475 Affinity Capture-Western; Reconstituted Complex
IWS1SUPT6H12080719141475 Affinity Capture-Western; Reconstituted Complex
WDR48SUPT6H12164919615732 Affinity Capture-MS
WDR48SUPT6H11269819615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107726
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7949'