AutismKB 2.0

Annotation Details for SUV39H1


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Basic Information Top
Gene Symbol:SUV39H1 ( KMT1A,MG44,SUV39H )
Gene Full Name: suppressor of variegation 3-9 homolog 1 (Drosophila)
Band: Xp11.23
Quick LinksEntrez ID:6839; OMIM: 300254; Uniprot ID:SUV91_HUMAN; ENSEMBL ID: ENSG00000101945; HGNC ID: 11479
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000775IEA-chromosome, centromeric region-
GO:0000792IDA-heterochromatin18004385
GO:0000794TAS-condensed nuclear chromosome10202156
GO:0005634IDA-nucleus18004385
GO:0005652IEA-nuclear lamina-
GO:0005654TAS-nucleoplasm-
GO:0005677IDA-chromatin silencing complex18485871
GO:0033553IDA-rDNA heterochromatin18485871
GO ID Evidence Qualifier GO_term References
GO:0000976ISS-transcription regulatory region sequence-specific DNA binding-
GO:0003682TAS-chromatin binding10202156
GO:0005515IPI-protein binding10949293
GO:0008270IEA-zinc ion binding-
GO:0008757IDA-S-adenosylmethionine-dependent methyltransferase activity10949293
GO:0018024IDA-histone-lysine N-methyltransferase activity17707234
GO:0018024TAS-histone-lysine N-methyltransferase activity-
GO:0042054IDA-histone methyltransferase activity10949293
GO:0046974EXP-histone methyltransferase activity (H3-K9 specific)18485871
GO:0046974IDA-histone methyltransferase activity (H3-K9 specific)10949293
GO:0047485IPI-protein N-terminus binding19218236
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter21402781
GO:0000183IDA-chromatin silencing at rDNA18485871
GO:0000183TAS-chromatin silencing at rDNA-
GO:0006325TAS-chromatin organization10949293
GO:0006351IEA-transcription, DNA-templated-
GO:0006364IEA-rRNA processing-
GO:0006974IDA-cellular response to DNA damage stimulus23509280
GO:0007049IEA-cell cycle-
GO:0016032IEA-viral process-
GO:0030154IEA-cell differentiation-
GO:0036123ISS-histone H3-K9 dimethylation-
GO:0036124ISS-histone H3-K9 trimethylation-
GO:0042754ISS-negative regulation of circadian rhythm-
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0048511IEA-rhythmic process-
GO:0071456IDA-cellular response to hypoxia21402781
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SUV39H1PRDM110710814985713 Affinity Capture-Western
SUV39H1PRDM111270614985713 Affinity Capture-Western
SUV39H1RUNX111270612917624 16652147 Affinity Capture-Western; Co-purification; Reconstituted Complex
SUV39H1RUNX110730912917624 16652147 Affinity Capture-Western; Co-purification; Reconstituted Complex
SUV39H1RUNX310731216652147 Affinity Capture-Western
SUV39H1RUNX311270616652147 Affinity Capture-Western
SUV39H1DBC111270619218236 Affinity Capture-Western
SUV39H1DBC110798819218236 Affinity Capture-Western
SUV39H1DNMT110812312711675 17085482 Affinity Capture-Western
SUV39H1DNMT111270612711675 17085482 Affinity Capture-Western
SUV39H1DNMT3A10812512711675 Affinity Capture-Western; Reconstituted Complex
SUV39H1DNMT3A11270612711675 Affinity Capture-Western; Reconstituted Complex
SUV39H1DNMT3B10812615120635 Reconstituted Complex
SUV39H1DNMT3B11270615120635 Reconstituted Complex
SUV39H1MECOM10842318619962 18655152 Affinity Capture-Western; Reconstituted Complex
SUV39H1MECOM11270618619962 18655152 Affinity Capture-Western; Reconstituted Complex
SUV39H1HDAC110931511788710 Affinity Capture-Western; Reconstituted Complex
SUV39H1HDAC111270611788710 Affinity Capture-Western; Reconstituted Complex
SUV39H1HDAC210931611788710 Affinity Capture-Western; Reconstituted Complex
SUV39H1HDAC211270611788710 Affinity Capture-Western; Reconstituted Complex
SUV39H1HDLBP10931918648073 Affinity Capture-Western
SUV39H1HDLBP11270618648073 Affinity Capture-Western
SUV39H1SMAD511026515107829 Affinity Capture-Western
SUV39H1SMAD511270615107829 Affinity Capture-Western
SUV39H1MBD111032212711603 Affinity Capture-Western; Co-localization; Reconstituted Complex
SUV39H1MBD111270612711603 Affinity Capture-Western; Co-localization; Reconstituted Complex
SUV39H1MECP211270612399542 Affinity Capture-Western
SUV39H1MECP211036812399542 Affinity Capture-Western
SUV39H1MYOD111073716858404 Affinity Capture-Western; Reconstituted Complex
SUV39H1MYOD111270616858404 Affinity Capture-Western; Reconstituted Complex
SUV39H1RARA11270616449642 Affinity Capture-Western
SUV39H1RARA11184916449642 Affinity Capture-Western
SUV39H1RB111270611484059 11533237 Affinity Capture-Western; Reconstituted Complex
SUV39H1RB111186011484059 11533237 Affinity Capture-Western; Reconstituted Complex
SUV39H1RBBP411186311788710 Reconstituted Complex
SUV39H1RBBP411270611788710 Reconstituted Complex
SUV39H1RBBP711270611788710 Reconstituted Complex
SUV39H1RBBP711186611788710 Reconstituted Complex
SUV39H1RBL111186812588981 Affinity Capture-Western
SUV39H1RBL111270612588981 Affinity Capture-Western
SUV39H1RBL211186912588981 Affinity Capture-Western
SUV39H1RBL211270612588981 Affinity Capture-Western
SUV39H1SBF111270610848615 Affinity Capture-Western; Co-localization; Synthetic Rescue
SUV39H1SBF111221210848615 Affinity Capture-Western; Co-localization; Synthetic Rescue
CBX1SUV39H111270610202156 Affinity Capture-Western; Co-fractionation
CBX1SUV39H111615110202156 Affinity Capture-Western; Co-fractionation
HDAC3SUV39H111270611788710 Affinity Capture-Western; Reconstituted Complex
HDAC3SUV39H111436811788710 Affinity Capture-Western; Reconstituted Complex
CBX4SUV39H111410512101246 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CBX4SUV39H111270612101246 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
THRASUV39H111270612138181 Reconstituted Complex
THRASUV39H111292312138181 Reconstituted Complex
HDAC5SUV39H111533112242305 Affinity Capture-Western
HDAC5SUV39H111270612242305 Affinity Capture-Western
HDAC4SUV39H111270612242305 Affinity Capture-Western
HDAC4SUV39H111510612242305 Affinity Capture-Western
HDAC9SUV39H111270612242305 Affinity Capture-Western; Reconstituted Complex
HDAC9SUV39H111508312242305 Affinity Capture-Western; Reconstituted Complex
CBX5SUV39H111703012242305 12711603 16189514 Affinity Capture-Western; Two-hybrid
CBX5SUV39H111270612242305 12711603 16189514 Affinity Capture-Western; Two-hybrid
TAL1SUV39H111274915677454 Affinity Capture-Western
TAL1SUV39H111270615677454 Affinity Capture-Western
CNTN2SUV39H111270616409643 Affinity Capture-Western; Reconstituted Complex
CNTN2SUV39H111276316409643 Affinity Capture-Western; Reconstituted Complex
HIST1H3ASUV39H111394616409643 16449642 Biochemical Activity
HIST1H3ASUV39H111270616409643 16449642 Biochemical Activity
PRAM1SUV39H111270616449642 Affinity Capture-Western; Co-localization
PRAM1SUV39H112389416449642 Affinity Capture-Western; Co-localization
GFI1BSUV39H111270616688220 Affinity Capture-Western
GFI1BSUV39H111392416688220 Affinity Capture-Western
CABIN1SUV39H111707017172641 Affinity Capture-Western; Reconstituted Complex
CABIN1SUV39H111270617172641 Affinity Capture-Western; Reconstituted Complex
SIRT1SUV39H111270618004385 19218236 Affinity Capture-Western
SIRT1SUV39H111698318004385 19218236 Affinity Capture-Western
RRP8SUV39H111695418485871 Affinity Capture-Western
RRP8SUV39H111270618485871 Affinity Capture-Western
TATSUV39H111270618498648 Affinity Capture-Western
TATSUV39H111276118498648 Affinity Capture-Western
ESCO2SUV39H112760518501190 Affinity Capture-Western
ESCO2SUV39H111270618501190 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1099440
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5105'