AutismKB 2.0

Annotation Details for SYN1


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Basic Information Top
Gene Symbol:SYN1 ( SYN1a,SYN1b,SYNI )
Gene Full Name: synapsin I
Band: Xp11.3-p11.23
Quick LinksEntrez ID:6853; OMIM: 313440; Uniprot ID:SYN1_HUMAN; ENSEMBL ID: ENSG00000008056; HGNC ID: 11494
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000795IEA-synaptonemal complex-
GO:0005794IEA-Golgi apparatus-
GO:0005829IEA-cytosol-
GO:0008021TAS-synaptic vesicle16141272
GO:0014069IEA-postsynaptic density-
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0043195IEA-terminal bouton-
GO:0043209IEA-myelin sheath-
GO:0048786IEA-presynaptic active zone-
GO:0098993IEA-anchored component of synaptic vesicle membrane-
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0003824IEA-catalytic activity-
GO:0005215TAS-transporter activity2110562
GO:0005515IPI-protein binding22163275
GO:0005524TAS-ATP binding15217342
GO:0019901ISS-protein kinase binding-
GO:0048306IEA-calcium-dependent protein binding-
GO ID Evidence Qualifier GO_term References
GO:0007268TAS-chemical synaptic transmission2110562
GO:0007269IEA-neurotransmitter secretion-
GO:0046928TAS-regulation of neurotransmitter secretion21563316
GO:0097091IEA-synaptic vesicle clustering-
GO:2000300NAS-regulation of synaptic vesicle exocytosis10099709
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SYN1AMPH11271910899172 Affinity Capture-Western
SYN1AMPH10677010899172 Affinity Capture-Western
SYN1BIN111271910899172 Affinity Capture-Western
SYN1BIN110677110899172 Affinity Capture-Western
SYN1BLM11271915829507 Two-hybrid
SYN1BLM10711015829507 Two-hybrid
SYN1CRK11271910899172 Affinity Capture-Western
SYN1CRK10778810899172 Affinity Capture-Western
SYN1GRB21091428022809 Reconstituted Complex
SYN1GRB21127198022809 Reconstituted Complex
SYN1NOS111090511867766 Reconstituted Complex
SYN1NOS111271911867766 Reconstituted Complex
SYN1PARK211110511431533 Affinity Capture-Western
SYN1PARK211271911431533 Affinity Capture-Western
SYN1PIK3R111271910899172 Affinity Capture-Western
SYN1PIK3R111131310899172 Affinity Capture-Western
SYN1RASA111271910899172 Affinity Capture-Western
SYN1RASA111185610899172 Affinity Capture-Western
SYN1SH3GL211235312456676 Reconstituted Complex
SYN1SH3GL211271912456676 Reconstituted Complex
SYN1SRC11259210899172 Affinity Capture-Western
SYN1SRC11271910899172 Affinity Capture-Western
SYN2SYN111271910358015 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYN2SYN111272010358015 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCF1SYN157572410899172 Affinity Capture-Western
NCF1SYN111271910899172 Affinity Capture-Western
NOS1APSYN111507111867766 Affinity Capture-Western; Reconstituted Complex
NOS1APSYN111271911867766 Affinity Capture-Western; Reconstituted Complex
KAT5SYN111271916169070 Two-hybrid
KAT5SYN111577916169070 Two-hybrid
SYN1SYN111271916169070 Two-hybrid
VIMSYN111271916169070 Two-hybrid
VIMSYN111327216169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98460
  • Data Attributes: MGI curated and HomoloGene calculated
No data