AutismKB 2.0

Annotation Details for SYP


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Basic Information Top
Gene Symbol:SYP ( MRXSYP )
Gene Full Name: synaptophysin
Band: Xp11.23
Quick LinksEntrez ID:6855; OMIM: 313475; Uniprot ID:SYPH_HUMAN; ENSEMBL ID: ENSG00000102003; HGNC ID: 11506
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0008021ISS-synaptic vesicle-
GO:0030054IEA-cell junction-
GO:0030285IBA-integral component of synaptic vesicle membrane-
GO:0030285NAS-integral component of synaptic vesicle membrane1975480
GO:0031594IEA-neuromuscular junction-
GO:0042734IEA-presynaptic membrane-
GO:0043005ISS-neuron projection-
GO:0043195IEA-terminal bouton-
GO:0048786IEA-presynaptic active zone-
GO:0060076IEA-excitatory synapse-
GO ID Evidence Qualifier GO_term References
GO:0005215IEA-transporter activity-
GO:0015485IDA-cholesterol binding10620806
GO:0042169IEA-SH2 domain binding-
GO:0042802IEA-identical protein binding-
GO:0043621TAS-protein self-association15217342
GO ID Evidence Qualifier GO_term References
GO:0006897ISS-endocytosis-
GO:0016188NAS-synaptic vesicle maturation10620806
GO:0048168IBA-regulation of neuronal synaptic plasticity-
GO:0048169ISS-regulation of long-term neuronal synaptic plasticity-
GO:0048172ISS-regulation of short-term neuronal synaptic plasticity-
GO:0048488IEA-synaptic vesicle endocytosis-
GO:0048499NAS-synaptic vesicle membrane organization10620806
GO:0071310IEA-cellular response to organic substance-
GO:2000474ISS-regulation of opioid receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SYPAP1G110667312498786 Affinity Capture-Western; Two-hybrid
SYPAP1G111272112498786 Affinity Capture-Western; Two-hybrid
SYPEPOR1083717534299 Reconstituted Complex
SYPEPOR1127217534299 Reconstituted Complex
SYPGRB21091427534299 Affinity Capture-Western
SYPGRB21127217534299 Affinity Capture-Western
SYPSIAH111237211786535 Reconstituted Complex
SYPSIAH111272111786535 Reconstituted Complex
SYPSIAH211237311786535 Reconstituted Complex; Two-hybrid
SYPSIAH211272111786535 Reconstituted Complex; Two-hybrid
SYPSTX1A1126767553862 Affinity Capture-Western
SYPSTX1A1127217553862 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SYPrs3817678 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:98467
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031104-2'