AutismKB 2.0

Annotation Details for SYT4


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Basic Information Top
Gene Symbol:SYT4 ( HsT1192,KIAA1342 )
Gene Full Name: synaptotagmin IV
Band: 18q12.3
Quick LinksEntrez ID:6860; OMIM: 600103; Uniprot ID:SYT4_HUMAN; ENSEMBL ID: ENSG00000132872; HGNC ID: 11512
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IBA-plasma membrane-
GO:0005886IDA-plasma membrane-
GO:0030054IEA-cell junction-
GO:0030173NAS-integral component of Golgi membrane26750488
GO:0030285NAS-integral component of synaptic vesicle membrane26750488
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0032127NAS-dense core granule membrane26750488
GO:0043025IEA-neuronal cell body-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0044306IEA-neuron projection terminus-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0097449IEA-astrocyte projection-
GO:1990742IEA-microvesicle-
GO ID Evidence Qualifier GO_term References
GO:0001786IEA-phosphatidylserine binding-
GO:0005509IBANOTcalcium ion binding-
GO:0005515IPI-protein binding16189514
GO:0005544IBANOTcalcium-dependent phospholipid binding-
GO:0017075IEA-syntaxin-1 binding-
GO:0019905IBA-syntaxin binding-
GO:0030276IBA-clathrin binding-
GO:0030348IEA-syntaxin-3 binding-
GO:0042803IEA-protein homodimerization activity-
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0006906IBA-vesicle fusion-
GO:0007420IEA-brain development-
GO:0007613IEA-memory-
GO:0014049IEA-positive regulation of glutamate secretion-
GO:0014059IEA-regulation of dopamine secretion-
GO:0017158IBANOTregulation of calcium ion-dependent exocytosis-
GO:0030100IEA-regulation of endocytosis-
GO:0031339IEA-negative regulation of vesicle fusion-
GO:0033604IGI-negative regulation of catecholamine secretion20735850
GO:0045955NAS-negative regulation of calcium ion-dependent exocytosis21153436
GO:0045956NAS-positive regulation of calcium ion-dependent exocytosis21153436
GO:0046929IEA-negative regulation of neurotransmitter secretion-
GO:0048174IEA-negative regulation of short-term neuronal synaptic plasticity-
GO:0048791IBA-calcium ion-regulated exocytosis of neurotransmitter-
GO:0050709IEA-negative regulation of protein secretion-
GO:0061782IEA-vesicle fusion with vesicle-
GO:0061792IEA-secretory granule maturation-
GO:1903861IDA-positive regulation of dendrite extension23999003
GO:1905433IEA-negative regulation of retrograde trans-synaptic signaling by neuropeptide-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SYT4SGTA11234716189514 Two-hybrid
SYT4SGTA11272416189514 Two-hybrid
SYNCRIPSYT411575510734137 Reconstituted Complex
SYNCRIPSYT411272410734137 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101759
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7297'