AutismKB 2.0

Annotation Details for T


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:T ( MGC104817,TFT )
Gene Full Name: T, brachyury homolog (mouse)
Band: 6q27
Quick LinksEntrez ID:6862; OMIM: 601397; Uniprot ID:BRAC_HUMAN; ENSEMBL ID: ENSG00000164458; HGNC ID: 11515
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin21632880
GO:0005634IDA-nucleus22611028
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978ISS-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000980IDA-RNA polymerase II distal enhancer sequence-specific DNA binding21632880
GO:0001085ISS-RNA polymerase II transcription factor binding-
GO:0001102IPI-RNA polymerase II activating transcription factor binding22164283
GO:0001191ISS-transcriptional repressor activity, RNA polymerase II transcription factor binding-
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding8963900
GO:0003705IDA-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding21632880
GO ID Evidence Qualifier GO_term References
GO:0000122ISS-negative regulation of transcription from RNA polymerase II promoter-
GO:0001570IEA-vasculogenesis-
GO:0001756IEA-somitogenesis-
GO:0001839IEA-neural plate morphogenesis-
GO:0001843IEA-neural tube closure-
GO:0003007IDA-heart morphogenesis21632880
GO:0003257IDA-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation21632880
GO:0006351IEA-transcription, DNA-templated-
GO:0007165NAS-signal transduction8963900
GO:0007341IEA-penetration of zona pellucida-
GO:0007498TAS-mesoderm development8963900
GO:0007509IEA-mesoderm migration involved in gastrulation-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008595TAS-anterior/posterior axis specification, embryo8963900
GO:0014028IEA-notochord formation-
GO:0023019IEA-signal transduction involved in regulation of gene expression-
GO:0030509IEA-BMP signaling pathway-
GO:0036342IEA-post-anal tail morphogenesis-
GO:0048706IEA-embryonic skeletal system development-
GO:0060070IEA-canonical Wnt signaling pathway-
GO:0060349IEA-bone morphogenesis-
GO:0060395IEA-SMAD protein signal transduction-
GO:0061371IEA-determination of heart left/right asymmetry-
GO:0071300IEA-cellular response to retinoic acid-
GO:0090009NAS-primitive streak formation18593560
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98472
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081028-48'