AutismKB 2.0

Annotation Details for TAF4


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Basic Information Top
Gene Symbol:TAF4 ( FLJ41943,TAF2C,TAF2C1,TAF4A,TAFII130,TAFII135 )
Gene Full Name: TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
Band: 20q13.33
Quick LinksEntrez ID:6874; OMIM: 601796; Uniprot ID:TAF4_HUMAN; ENSEMBL ID: ENSG00000130699; HGNC ID: 11537
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin24289924
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005669IDA-transcription factor TFIID complex14580349
GO:0005829IDA-cytosol-
GO:0033276IDA-transcription factor TFTC complex9603525
GO:0043234IMP-protein complex15641800
GO:0071339IDA-MLL1 complex15960975
GO ID Evidence Qualifier GO_term References
GO:0001075IBAcontributes_totranscription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-
GO:0003677IDA-DNA binding15601843
GO:0003700IDAcontributes_totranscription factor activity, sequence-specific DNA binding9603525
GO:0003713TAS-transcription coactivator activity9192867
GO:0005515IPI-protein binding7729427
GO:0008134IBA-transcription factor binding-
GO:0017162IPI-aryl hydrocarbon receptor binding15641800
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001541IEA-ovarian follicle development-
GO:0006352IDA-DNA-templated transcription, initiation9603525
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006367IDA-transcription initiation from RNA polymerase II promoter9603525
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0016032IEA-viral process-
GO:0045893IDA-positive regulation of transcription, DNA-templated12771217
GO:0045944IBA-positive regulation of transcription from RNA polymerase II promoter-
GO:0051123IEA-RNA polymerase II transcriptional preinitiation complex assembly-
GO:1901796TAS-regulation of signal transduction by p53 class mediator-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TAF4CREB111273715703171 Affinity Capture-Western
TAF4CREB110777515703171 Affinity Capture-Western
TAF4CREM11273710409662 Reconstituted Complex
TAF4CREM10778010409662 Reconstituted Complex
TAF4KAT2A11273711406595 Affinity Capture-Western
TAF4KAT2A10891811406595 Affinity Capture-Western
TAF4GTF2A111273717643375 Affinity Capture-MS
TAF4GTF2A110921217643375 Affinity Capture-MS
TAF4GTF2A211273711564872 Reconstituted Complex
TAF4GTF2A210921311564872 Reconstituted Complex
TAF4SP11127379742090 Two-hybrid
TAF4SP11125509742090 Two-hybrid
TAF4TAF111273511564872 Reconstituted Complex
TAF4TAF111273711564872 Reconstituted Complex
TBPTAF41127379153318 12665565 17967894 19240132 Affinity Capture-Western; Co-purification; Reconstituted Complex
TBPTAF41127719153318 12665565 17967894 19240132 Affinity Capture-Western; Co-purification; Reconstituted Complex
TAF10TAF411273711406595 17643375 Affinity Capture-MS; Affinity Capture-Western
TAF10TAF411274411406595 17643375 Affinity Capture-MS; Affinity Capture-Western
TAF5TAF411273711406595 Affinity Capture-Western
TAF5TAF411274011406595 Affinity Capture-Western
SAP130TAF411273711406595 Affinity Capture-Western
SAP130TAF412273511406595 Affinity Capture-Western
SUPT3HTAF411404211406595 Affinity Capture-Western
SUPT3HTAF411273711406595 Affinity Capture-Western
TAF9TAF411273711564863 Affinity Capture-Western
TAF9TAF411274311564863 Affinity Capture-Western
TAF12TAF411273711564872 12237304 Co-crystal Structure; Far Western
TAF12TAF411274611564872 12237304 Co-crystal Structure; Far Western
TAF8TAF411273711564872 Far Western
TAF8TAF412620511564872 Far Western
TAF4TAF411273711564872 Far Western
CBX5TAF411273711959914 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CBX5TAF411703011959914 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TCF12TAF411273715333839 Reconstituted Complex
TCF12TAF411279815333839 Reconstituted Complex
ATF7TAF411273715735663 Affinity Capture-Western; Reconstituted Complex
ATF7TAF411620615735663 Affinity Capture-Western; Reconstituted Complex
TAF13TAF411273717643375 Affinity Capture-MS
TAF13TAF411274717643375 Affinity Capture-MS
TBPL1TAF411273717643375 Affinity Capture-MS
TBPL1TAF411489617643375 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
TAF4HTT13052511988536 TAFII130 interacts with htt.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2152346
  • Data Attributes: MGI curated and HomoloGene calculated
No data