AutismKB 2.0

Annotation Details for TAP1


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Basic Information Top
Gene Symbol:TAP1 ( ABC17,ABCB2,APT1,D6S114E,FLJ26666,FLJ41500,PSF1,RING4,TAP1*0102N,TAP1N )
Gene Full Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Band: 6p21.32
Quick LinksEntrez ID:6890; OMIM: 170260; Uniprot ID:TAP1_HUMAN; ENSEMBL ID: ENSG00000168394; HGNC ID: 43
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IEA-mitochondrion-
GO:0005783IDA-endoplasmic reticulum-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005815IDA-microtubule organizing center-
GO:0016020IDA-membrane19946888
GO:0016021IDA-integral component of membrane8955196
GO:0030176IDA-integral component of endoplasmic reticulum membrane7673167
GO:0030670TAS-phagocytic vesicle membrane-
GO:0033116TAS-endoplasmic reticulum-Golgi intermediate compartment membrane-
GO:0042825IDA-TAP complex11133832
GO:0043657IEA-host cell-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12213826
GO:0005524IDA-ATP binding7673167
GO:0005524IMP-ATP binding15793001
GO:0015197IGIcontributes_topeptide transporter activity7673167
GO:0015197IMP-peptide transporter activity17418234
GO:0015440IEA-peptide-transporting ATPase activity-
GO:0023029IPI-MHC class Ib protein binding10605026
GO:0042288IEA-MHC class I protein binding-
GO:0042605NAS-peptide antigen binding11133832
GO:0042803ISS-protein homodimerization activity-
GO:0043531IDA-ADP binding11532960
GO:0046978ISS-TAP1 binding-
GO:0046979IPI-TAP2 binding1538751
GO ID Evidence Qualifier GO_term References
GO:0002250IEA-adaptive immune response-
GO:0002474TAS-antigen processing and presentation of peptide antigen via MHC class I-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006952IEA-defense response-
GO:0015833IMP-peptide transport11133832
GO:0019060IMP-intracellular transport of viral protein in host cell7538543
GO:0019885IMP-antigen processing and presentation of endogenous peptide antigen via MHC class I11133832
GO:0046967IMP-cytosol to ER transport7538543
GO:0055085IEA-transmembrane transport-
GO:1990668TAS-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TAP1COPB111275311884415 Affinity Capture-Western
TAP1COPB110771011884415 Affinity Capture-Western
TAP1PDIA31091809545232 Affinity Capture-MS
TAP1PDIA31127539545232 Affinity Capture-MS
TAP1HLA-A11275311884415 Affinity Capture-Western
TAP1HLA-A10935011884415 Affinity Capture-Western
TAP1HLA-G1093809103419 Affinity Capture-Western
TAP1HLA-G1127539103419 Affinity Capture-Western
TAP1MDFI11275316189514 Two-hybrid
TAP1MDFI11035316189514 Two-hybrid
TAP2TAP111275311381133 Reconstituted Complex
TAP2TAP111275411381133 Reconstituted Complex
COPGTAP111275311884415 Affinity Capture-Western
COPGTAP111649611884415 Affinity Capture-Western
TAPBPTAP111275311884415 12213826 Affinity Capture-Western; Reconstituted Complex
TAPBPTAP111275511884415 12213826 Affinity Capture-Western; Reconstituted Complex
KRTAP4-12TAP111275316189514 Two-hybrid
KRTAP4-12TAP112375616189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
TAP1rs1800453, rs4148880 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:98483
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050517-43'