AutismKB 2.0

Annotation Details for TCF7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TCF7 ( FLJ36364,MGC47735,TCF-1 )
Gene Full Name: transcription factor 7 (T-cell specific, HMG-box)
Band: 5q31.1
Quick LinksEntrez ID:6932; OMIM: 189908; Uniprot ID:TCF7_HUMAN; ENSEMBL ID: ENSG00000081059; HGNC ID: 11639
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18579517
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IBA-transcription factor complex-
GO:0005719IEA-nuclear euchromatin-
GO:0016604IDA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0001047IEA-core promoter binding-
GO:0001227IEA-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0005515IPI-protein binding9783587
GO:0008013IDA-beta-catenin binding9488439
GO:0043565IBA-sequence-specific DNA binding-
GO:0044212IDA-transcription regulatory region DNA binding18579517
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter1569101
GO:0006955TAS-immune response1569101
GO:0021915IEA-neural tube development-
GO:0030538IEA-embryonic genitalia morphogenesis-
GO:0033153IEA-T cell receptor V(D)J recombination-
GO:0042127IEA-regulation of cell proliferation-
GO:0044336IEA-canonical Wnt signaling pathway involved in negative regulation of apoptotic process-
GO:0046632IEA-alpha-beta T cell differentiation-
GO:0048557IEA-embryonic digestive tract morphogenesis-
GO:0048619IEA-embryonic hindgut morphogenesis-
GO:0060070IBA-canonical Wnt signaling pathway-
GO:0071353IDA-cellular response to interleukin-418579517
GO:1904837TAS-beta-catenin-TCF complex assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DAZAP2TCF711279419304756 Affinity Capture-Western
DAZAP2TCF711514319304756 Affinity Capture-Western
SS18L1TCF711750520211142 Two-hybrid
SS18L1TCF711279420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98507
  • Data Attributes: MGI curated and HomoloGene calculated