AutismKB 2.0

Annotation Details for TCF12


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Basic Information Top
Gene Symbol:TCF12 ( HEB,HTF4,HsT17266,bHLHb20 )
Gene Full Name: transcription factor 12
Band: 15q21.3
Quick LinksEntrez ID:6938; OMIM: 600480; Uniprot ID:HTF4_HUMAN; ENSEMBL ID: ENSG00000140262; HGNC ID: 11623
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin21828274
GO:0005634IDA-nucleus21828274
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm21828274
GO:0016607IDA-nuclear speck-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0090575IDA-RNA polymerase II transcription factor complex11802795
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding11802795
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding11802795
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding11802795
GO:0005515IPI-protein binding11802795
GO:0008134IPI-transcription factor binding21828274
GO:0035326IC-enhancer binding21828274
GO:0035497IEA-cAMP response element binding-
GO:0042803IBA-protein homodimerization activity-
GO:0043425IPI-bHLH transcription factor binding21828274
GO:0044212IDAcontributes_totranscription regulatory region DNA binding11802795
GO:0046332IPI-SMAD binding21828274
GO:0046982IBA-protein heterodimerization activity-
GO:0070888IEA-E-box binding-
GO:0071837IEA-HMG box domain binding-
GO ID Evidence Qualifier GO_term References
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter8163514
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006955TAS-immune response1312219
GO:0007517TAS-muscle organ development1312219
GO:0045666IBA-positive regulation of neuron differentiation-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter11802795
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TCF12RUNX111279815333839 Affinity Capture-Western
TCF12RUNX110730915333839 Affinity Capture-Western
TCF12RUNX1T110731015333839 Affinity Capture-Western; Reconstituted Complex
TCF12RUNX1T111279815333839 Affinity Capture-Western; Reconstituted Complex
TCF12CREBBP11279815333839 Reconstituted Complex
TCF12CREBBP10777715333839 Reconstituted Complex
TCF12EP30010834715333839 Reconstituted Complex
TCF12EP30011279815333839 Reconstituted Complex
TCF12ID11127989242638 Two-hybrid
TCF12ID11096239242638 Two-hybrid
TCF12ID21127989242638 Two-hybrid
TCF12ID21096249242638 Two-hybrid
TCF12ID31096259242638 Two-hybrid
TCF12ID31127989242638 Two-hybrid
TCF12TAF411273715333839 Reconstituted Complex
TCF12TAF411279815333839 Reconstituted Complex
TCF12TAL111274916407974 Affinity Capture-MS
TCF12TAL111279816407974 Affinity Capture-MS
TCF12TAL211275020211142 Two-hybrid
TCF12TAL211279820211142 Two-hybrid
TCF12TBP11277115333839 Reconstituted Complex
TCF12TBP11279815333839 Reconstituted Complex
ASCL4TCF1212573714516699 Two-hybrid
ASCL4TCF1211279814516699 Two-hybrid
TCF23TCF1212733014516699 Two-hybrid
TCF23TCF1211279814516699 Two-hybrid
OLIG3TCF1212795114516699 Two-hybrid
OLIG3TCF1211279814516699 Two-hybrid
PRSS23TCF1211627916169070 Two-hybrid
PRSS23TCF1211279816169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101877
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040516-11'