AutismKB 2.0

Annotation Details for BUB1


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Basic Information Top
Gene Symbol:BUB1 ( BUB1A,BUB1L,hBUB1 )
Gene Full Name: budding uninhibited by benzimidazoles 1 homolog (yeast)
Band: 2q13
Quick LinksEntrez ID:699; OMIM: 602452; Uniprot ID:BUB1_HUMAN; ENSEMBL ID: ENSG00000169679; HGNC ID: 1148
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000776IDA-kinetochore15020684
GO:0000777IDA-condensed chromosome kinetochore19465021
GO:0000942IDA-condensed nuclear chromosome outer kinetochore24055156
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0004672TAS-protein kinase activity10198256
GO:0004674IEA-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding10198256
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0006468IEA-protein phosphorylation-
GO:0006915IEA-apoptotic process-
GO:0007062TAS-sister chromatid cohesion-
GO:0007063IDA-regulation of sister chromatid cohesion15723797
GO:0007093TAS-mitotic cell cycle checkpoint9521327
GO:0007094IEA-mitotic spindle assembly checkpoint-
GO:0008283IEA-cell proliferation-
GO:0016032IEA-viral process-
GO:0051301IEA-cell division-
GO:0051754IBA-meiotic sister chromatid cohesion, centromeric-
GO:0051983IMP-regulation of chromosome segregation19487456
GO:0071173IDA-spindle assembly checkpoint15020684
GO:0071173IMP-spindle assembly checkpoint19487456
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BUB1APC10716411283619 Affinity Capture-Western; Biochemical Activity
BUB1APC10682111283619 Affinity Capture-Western; Biochemical Activity
RAE1BUB110716411352911 Affinity Capture-Western
RAE1BUB111405411352911 Affinity Capture-Western
HDAC1BUB110716415388328 Affinity Capture-Western; Co-purification
HDAC1BUB110931515388328 Affinity Capture-Western; Co-purification
ARIH2BUB110716416189514 Two-hybrid
ARIH2BUB111569416189514 Two-hybrid
CRKBUB110716416189514 Two-hybrid
CRKBUB110778816189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1100510
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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