AutismKB 2.0

Annotation Details for DYNLT1


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Basic Information Top
Gene Symbol:DYNLT1 ( CW-1,MGC111571,TCTEL1,tctex-1 )
Gene Full Name: dynein, light chain, Tctex-type 1
Band: 6q25.3
Quick LinksEntrez ID:6993; OMIM: 601554; Uniprot ID:DYLT1_HUMAN; ENSEMBL ID: ENSG00000146425; HGNC ID: 11697
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005794IEA-Golgi apparatus-
GO:0005819IEA-spindle-
GO:0005868IDA-cytoplasmic dynein complex25205765
GO:0005868ISS-cytoplasmic dynein complex-
GO:0005881IDA-cytoplasmic microtubule21262767
GO:0034774TAS-secretory granule lumen-
GO:0043657IEA-host cell-
GO:0099503IDA-secretory vesicle21262767
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0003774IEA-motor activity-
GO:0005515IPI-protein binding10644691
GO:0042802IPI-identical protein binding17965411
GO ID Evidence Qualifier GO_term References
GO:0000132ISS-establishment of mitotic spindle orientation-
GO:0008277ISS-regulation of G-protein coupled receptor protein signaling pathway-
GO:0019060IMP-intracellular transport of viral protein in host cell18647839
GO:0043087IEA-regulation of GTPase activity-
GO:0043312TAS-neutrophil degranulation-
GO:0046718IEA-viral entry into host cell-
GO:0048812IEA-neuron projection morphogenesis-
GO:0050768ISS-negative regulation of neurogenesis-
GO:0051301IEA-cell division-
GO:0051493IEA-regulation of cytoskeleton organization-
GO:0075521IEA-microtubule-dependent intracellular transport of viral material towards nucleus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DYNLT1DYNC1I111285312475239 Two-hybrid
DYNLT1DYNC1I110811812475239 Two-hybrid
DYNLT1PVR11285311751937 Affinity Capture-Western; Two-hybrid
DYNLT1PVR11177511751937 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98643
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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