AutismKB 2.0

Annotation Details for TDO2


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Basic Information Top
Gene Symbol:TDO2 ( TDO,TPH2,TRPO )
Gene Full Name: tryptophan 2,3-dioxygenase
Band: 4q32.1
Quick LinksEntrez ID:6999; OMIM: 191070; Uniprot ID:T23O_HUMAN; ENSEMBL ID: ENSG00000151790; HGNC ID: 11708
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004833IBA-tryptophan 2,3-dioxygenase activity-
GO:0004833IDA-tryptophan 2,3-dioxygenase activity27762317
GO:0004833TAS-tryptophan 2,3-dioxygenase activity-
GO:0005515IPI-protein binding16189514
GO:0016597IEA-amino acid binding-
GO:0019825IEA-oxygen binding-
GO:0020037IBA-heme binding-
GO:0020037IDA-heme binding27762317
GO:0042802IPI-identical protein binding25416956
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006569TAS-tryptophan catabolic process-
GO:0019441IDA-tryptophan catabolic process to kynurenine27762317
GO:0019441IEA-tryptophan catabolic process to kynurenine-
GO:0019442IBA-tryptophan catabolic process to acetyl-CoA-
GO:0051289IDA-protein homotetramerization27762317
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ASMTLTDO211417816189514 Two-hybrid
ASMTLTDO211285816189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
TDO2rs2271537 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1928486
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1187'