AutismKB 2.0

Annotation Details for TEC


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Basic Information Top
Gene Symbol:TEC ( MGC126760,MGC126762,PSCTK4 )
Gene Full Name: tec protein tyrosine kinase
Band: 4p12-p11
Quick LinksEntrez ID:7006; OMIM: 600583; Uniprot ID:TEC_HUMAN; ENSEMBL ID: ENSG00000135605; HGNC ID: 11719
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005856IDA-cytoskeleton9299487
GO:0005886IDA-plasma membrane-
GO:0031234IBA-extrinsic component of cytoplasmic side of plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0004715IDA-non-membrane spanning protein tyrosine kinase activity10518561
GO:0005102IBANOTreceptor binding-
GO:0005515IPI-protein binding8892607
GO:0005524IEA-ATP binding-
GO:0005543NAS-phospholipid binding10518561
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0002250IEA-adaptive immune response-
GO:0006468TAS-protein phosphorylation7934162
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007229IDA-integrin-mediated signaling pathway9652744
GO:0010543IDA-regulation of platelet activation9299487
GO:0018108IDA-peptidyl-tyrosine phosphorylation10518561
GO:0030154IBA-cell differentiation-
GO:0035556IEA-intracellular signal transduction-
GO:0038083IMP-peptidyl-tyrosine autophosphorylation10518561
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0042127IBA-regulation of cell proliferation-
GO:0042246IBA-tissue regeneration-
GO:0045087IBA-innate immune response-
GO:0050731IDA-positive regulation of peptidyl-tyrosine phosphorylation10518561
GO:0050853IDA-B cell receptor signaling pathway10518561
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TECRHOA10688012515866 Reconstituted Complex
TECRHOA11286512515866 Reconstituted Complex
TECDOK111286511071635 11825908 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TECDOK110813111071635 11825908 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TECGNA1210903012515866 Affinity Capture-Western; Phenotypic Enhancement
TECGNA1211286512515866 Affinity Capture-Western; Phenotypic Enhancement
TECJAK11099199178903 Affinity Capture-Western
TECJAK11128659178903 Affinity Capture-Western
TECJAK21099209178903 9473212 Affinity Capture-Western; Biochemical Activity
TECJAK21128659178903 9473212 Affinity Capture-Western; Biochemical Activity
TECKIT1100157526158 11071635 Affinity Capture-Western; Reconstituted Complex
TECKIT1128657526158 11071635 Affinity Capture-Western; Reconstituted Complex
TECLYN11024511071635 Affinity Capture-Western
TECLYN11286511071635 Affinity Capture-Western
TECPIK3R21113149178903 Two-hybrid
TECPIK3R21128659178903 Two-hybrid
TECPRLR11160311328862 Affinity Capture-Western; Reconstituted Complex
TECPRLR11286511328862 Affinity Capture-Western; Reconstituted Complex
TECRAC111181711328862 Phenotypic Enhancement
TECRAC111286511328862 Phenotypic Enhancement
WASTEC1132938892607 Reconstituted Complex
WASTEC1128658892607 Reconstituted Complex
SOCS1TEC1142039341160 Reconstituted Complex; Two-hybrid
SOCS1TEC1128659341160 Reconstituted Complex; Two-hybrid
VAV1TEC11325211328862 Affinity Capture-Western
VAV1TEC11286511328862 Affinity Capture-Western
ARHGEF12TEC11694512515866 Biochemical Activity; Phenotypic Enhancement
ARHGEF12TEC11286512515866 Biochemical Activity; Phenotypic Enhancement
GNA13TEC11591412515866 Phenotypic Enhancement
GNA13TEC11286512515866 Phenotypic Enhancement
IKBKGTEC11408920098747 Reconstituted Complex
IKBKGTEC11286520098747 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98662
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7499'