AutismKB 2.0

Annotation Details for TMBIM6


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Basic Information Top
Gene Symbol:TMBIM6 ( BAXI1,BI-1,TEGT )
Gene Full Name: transmembrane BAX inhibitor motif containing 6
Band: 12q13.12
Quick LinksEntrez ID:7009; OMIM: 600748; Uniprot ID:BI1_HUMAN; ENSEMBL ID: ENSG00000139644; HGNC ID: 11723
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus8530040
GO:0005737IDA-cytoplasm9660918
GO:0005783IDA-endoplasmic reticulum19328063
GO:0005789IDA-endoplasmic reticulum membrane9660918
GO:0005887TAS-integral component of plasma membrane10087504
GO:0016020IDA-membrane19946888
GO:0016021NAS-integral component of membrane9660918
GO:0031966IDA-mitochondrial membrane9660918
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9660918
GO:0019899IPI-enzyme binding19328063
GO:0031625IPI-ubiquitin protein ligase binding21068390
GO:0060698IDA-endoribonuclease inhibitor activity19328063
GO ID Evidence Qualifier GO_term References
GO:0006914IEA-autophagy-
GO:0006986IEA-response to unfolded protein-
GO:0010523IDA-negative regulation of calcium ion transport into cytosol26582200
GO:0032091IDA-negative regulation of protein binding19328063
GO:0032469IEA-endoplasmic reticulum calcium ion homeostasis-
GO:0043066IGI-negative regulation of apoptotic process9660918
GO:0051025IEA-negative regulation of immunoglobulin secretion-
GO:0060702IDA-negative regulation of endoribonuclease activity19328063
GO:0070059IEA-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-
GO:1902065IDA-response to L-glutamate21075086
GO:1902236IDA-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway21075086
GO:1903298IDA-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway21075086
GO:1904721IDA-negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response19328063
GO:1990441IEA-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-
GO:2001234IDA-negative regulation of apoptotic signaling pathway21075086
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TMBIM6BCL21070689660918 Affinity Capture-Western
TMBIM6BCL21128689660918 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99682
  • Data Attributes: MGI curated and HomoloGene calculated
No data