AutismKB 2.0

Annotation Details for TFAP2C


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Basic Information Top
Gene Symbol:TFAP2C ( AP2-GAMMA,ERF1,TFAP2G,hAP-2g )
Gene Full Name: transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Band: 20q13.31
Quick LinksEntrez ID:7022; OMIM: 601602; Uniprot ID:AP2C_HUMAN; ENSEMBL ID: ENSG00000087510; HGNC ID: 11744
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus24413532
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005739IDA-mitochondrion-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000977IBA-RNA polymerase II regulatory region sequence-specific DNA binding-
GO:0001047IDA-core promoter binding24413532
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding11278550
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding11278550
GO:0003677IDA-DNA binding12072434
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9113991
GO:0005515IPI-protein binding11694877
GO:0046983IDA-protein dimerization activity12072434
GO ID Evidence Qualifier GO_term References
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007267TAS-cell-cell signaling9113991
GO:0008584IEP-male gonad development17848411
GO:0040029IMP-regulation of gene expression, epigenetic24413532
GO:0042127IBA-regulation of cell proliferation-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter22735262
GO:0045944TAS-positive regulation of transcription from RNA polymerase II promoter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CITED4TFAP2C11288011744733 Reconstituted Complex
CITED4TFAP2C12787511744733 Reconstituted Complex
CITED2TFAP2C11564911744733 12586840 Reconstituted Complex; Two-hybrid
CITED2TFAP2C11288011744733 12586840 Reconstituted Complex; Two-hybrid
TP53TFAP2C11288012226108 Reconstituted Complex
TP53TFAP2C11301012226108 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106032
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041212-61'