AutismKB 2.0

Annotation Details for NR2F1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NR2F1 ( COUP-TFI,EAR-3,EAR3,ERBAL3,NR2F2,SVP44,TCFCOUP1,TFCOUP1 )
Gene Full Name: nuclear receptor subfamily 2, group F, member 1
Band: 5q15
Quick LinksEntrez ID:7025; OMIM: 132890; Uniprot ID:COT1_HUMAN; ENSEMBL ID: ENSG00000175745; HGNC ID: 7975
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10644740
GO:0005654TAS-nucleoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding10644740
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding10644740
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding10644740
GO:0003707IEA-steroid hormone receptor activity-
GO:0003713TAS-transcription coactivator activity2739739
GO:0004879IEA-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-
GO:0005515IPI-protein binding11043578
GO:0008270IEA-zinc ion binding-
GO:0043565IDA-sequence-specific DNA binding10644740
GO:0044323IEA-retinoic acid-responsive element binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter10644740
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0007165TAS-signal transduction2739739
GO:0010977IEA-negative regulation of neuron projection development-
GO:0030522IEA-intracellular receptor signaling pathway-
GO:0043401IEA-steroid hormone mediated signaling pathway-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NR2F1AHR10669910620335 Reconstituted Complex
NR2F1AHR11288310620335 Reconstituted Complex
NR2F1ESR110840312093745 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NR2F1ESR111288312093745 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NR2F1GTF2B1128831517211 Reconstituted Complex
NR2F1GTF2B1092141517211 Reconstituted Complex
NR2F1ISL111288311043578 Reconstituted Complex
NR2F1ISL110987711043578 Reconstituted Complex
NR2F1SP11125509388268 15849318 Reconstituted Complex
NR2F1SP11128839388268 15849318 Reconstituted Complex
COPS2NR2F111288310207062 Reconstituted Complex
COPS2NR2F111472910207062 Reconstituted Complex
GRIP1NR2F111699510652338 Two-hybrid
GRIP1NR2F111288310652338 Two-hybrid
NCOA3NR2F111288310652338 Two-hybrid
NCOA3NR2F111384110652338 Two-hybrid
BCL11BNR2F112234310744719 15849318 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BCL11BNR2F111288310744719 15849318 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BCL11ANR2F111973710744719 Reconstituted Complex; Two-hybrid
BCL11ANR2F111288310744719 Reconstituted Complex; Two-hybrid
PHB2NR2F111288315140878 Reconstituted Complex
PHB2NR2F111645915140878 Reconstituted Complex
CBX5NR2F111703015849318 Reconstituted Complex
CBX5NR2F111288315849318 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352451
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1438'