AutismKB 2.0

Annotation Details for NR2F2


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Basic Information Top
Gene Symbol:NR2F2 ( ARP1,COUPTFB,COUPTFII,MGC117452,SVP40,TFCOUP2 )
Gene Full Name: nuclear receptor subfamily 2, group F, member 2
Band: 15q26.2
Quick LinksEntrez ID:7026; OMIM: 107773; Uniprot ID:COT2_HUMAN; ENSEMBL ID: ENSG00000185551; HGNC ID: 7976
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus19210544
GO ID Evidence Qualifier GO_term References
GO:0001972IDA-retinoic acid binding18798693
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding9343308
GO:0003707IEA-steroid hormone receptor activity-
GO:0003714TAS-transcription corepressor activity1899293
GO:0004879IDA-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding18798693
GO:0005515IPI-protein binding18798693
GO:0008270IEA-zinc ion binding-
GO:0042803IPI-protein homodimerization activity18798693
GO:0043565IDA-sequence-specific DNA binding9343308
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter9343308
GO:0001764IEA-neuron migration-
GO:0001893IEA-maternal placenta development-
GO:0001937IMP-negative regulation of endothelial cell proliferation19210544
GO:0003084IEA-positive regulation of systemic arterial blood pressure-
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter1899293
GO:0006629TAS-lipid metabolic process1899293
GO:0007165TAS-signal transduction1899293
GO:0007519IEA-skeletal muscle tissue development-
GO:0009566IEA-fertilization-
GO:0009952IEA-anterior/posterior pattern specification-
GO:0009956IEA-radial pattern formation-
GO:0010596IMP-negative regulation of endothelial cell migration19210544
GO:0030522IEA-intracellular receptor signaling pathway-
GO:0030900IEA-forebrain development-
GO:0032355IEA-response to estradiol-
GO:0043401IEA-steroid hormone mediated signaling pathway-
GO:0045736IDA-negative regulation of cyclin-dependent protein serine/threonine kinase activity19210544
GO:0045892IDA-negative regulation of transcription, DNA-templated19210544
GO:0045893IDA-positive regulation of transcription, DNA-templated18798693
GO:0045893IMP-positive regulation of transcription, DNA-templated18815287
GO:0048514IEA-blood vessel morphogenesis-
GO:0060173IEA-limb development-
GO:0060674IEA-placenta blood vessel development-
GO:0060707IEA-trophoblast giant cell differentiation-
GO:0060849IMP-regulation of transcription involved in lymphatic endothelial cell fate commitment18815287
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NR2F2NR2F611288410318855 Reconstituted Complex; Two-hybrid
NR2F2NR2F610837510318855 Reconstituted Complex; Two-hybrid
NR2F2NR3C110916514739255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NR2F2NR3C111288414739255 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NR2F2HDAC110931510704340 Phenotypic Enhancement; Reconstituted Complex
NR2F2HDAC111288410704340 Phenotypic Enhancement; Reconstituted Complex
NR2F2LCK1128848910285 Reconstituted Complex; Two-hybrid
NR2F2LCK1101248910285 Reconstituted Complex; Two-hybrid
NR2F2MYOD11128849826778 Reconstituted Complex
NR2F2MYOD11107379826778 Reconstituted Complex
PHB2NR2F211288415140878 Reconstituted Complex
PHB2NR2F211645915140878 Reconstituted Complex
TRIP4NR2F211473520211142 Two-hybrid
TRIP4NR2F211288420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352452
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-252'