AutismKB 2.0

Annotation Details for TGFB1I1


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Basic Information Top
Gene Symbol:TGFB1I1 ( ARA55,HIC-5,HIC5,TSC-5 )
Gene Full Name: transforming growth factor beta 1 induced transcript 1
Band: 16p11.2
Quick LinksEntrez ID:7041; OMIM: 602353; Uniprot ID:TGFI1_HUMAN; ENSEMBL ID: ENSG00000140682; HGNC ID: 11767
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IDA-intracellular10075738
GO:0005737IEA-cytoplasm-
GO:0005856IEA-cytoskeleton-
GO:0005925IDA-focal adhesion21423176
GO:0016363IEA-nuclear matrix-
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO ID Evidence Qualifier GO_term References
GO:0003713IDA-transcription coactivator activity10075738
GO:0003713NAS-transcription coactivator activity15572661
GO:0005515IPI-protein binding9756887
GO:0046872IEA-metal ion binding-
GO:0048495IPI-Roundabout binding19855388
GO:0050681IPI-androgen receptor binding10075738
GO:0050681NAS-androgen receptor binding15572661
GO:0070411IPI-I-SMAD binding18762808
GO ID Evidence Qualifier GO_term References
GO:0006366TAS-transcription from RNA polymerase II promoter10075738
GO:0007155TAS-cell adhesion9422762
GO:0008285TAS-negative regulation of cell proliferation7929412
GO:0009408IEA-response to heat-
GO:0010718IDA-positive regulation of epithelial to mesenchymal transition18762808
GO:0016055IEA-Wnt signaling pathway-
GO:0016331IEA-morphogenesis of embryonic epithelium-
GO:0030511IDA-positive regulation of transforming growth factor beta receptor signaling pathway18762808
GO:0030512IDA-negative regulation of transforming growth factor beta receptor signaling pathway18762808
GO:0030521NAS-androgen receptor signaling pathway15572661
GO:0030579IDA-ubiquitin-dependent SMAD protein catabolic process18762808
GO:0030855IEA-epithelial cell differentiation-
GO:0045165IEA-cell fate commitment-
GO:0045599IEA-negative regulation of fat cell differentiation-
GO:0045893IDA-positive regulation of transcription, DNA-templated10075738
GO:0045893NAS-positive regulation of transcription, DNA-templated15572661
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TGFB1I1AR11289911779876 11856738 Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
TGFB1I1AR10686211779876 11856738 Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
TGFB1I1CSK1078329858471 Reconstituted Complex
TGFB1I1CSK1128999858471 Reconstituted Complex
TGFB1I1PTK2B1084809422762 9858471 11856738 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TGFB1I1PTK2B1128999422762 9858471 11856738 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TGFB1I1NR3C110916510848625 Two-hybrid
TGFB1I1NR3C111289910848625 Two-hybrid
TGFB1I1HSPB110954711546764 Affinity Capture-Western; Two-hybrid
TGFB1I1HSPB111289911546764 Affinity Capture-Western; Two-hybrid
TGFB1I1PTK21117199422762 9858471 11463817 Affinity Capture-Western; Reconstituted Complex
TGFB1I1PTK21128999422762 9858471 11463817 Affinity Capture-Western; Reconstituted Complex
TGFB1I1PTPN1211174610092676 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TGFB1I1PTPN1211289910092676 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TGFB1I1PXN11178711463817 Affinity Capture-Western
TGFB1I1PXN11289911463817 Affinity Capture-Western
TGFB1I1SLC6A311242212177201 Reconstituted Complex; Two-hybrid
TGFB1I1SLC6A311289912177201 Reconstituted Complex; Two-hybrid
VCLTGFB1I11132579858471 Reconstituted Complex
VCLTGFB1I11128999858471 Reconstituted Complex
VHLTGFB1I111326917353931 Affinity Capture-MS
VHLTGFB1I111289917353931 Affinity Capture-MS
CCNA1TGFB1I111441717353931 Affinity Capture-MS
CCNA1TGFB1I111289917353931 Affinity Capture-MS
No data
Gene Symbol Interactant Interaction ID References Description
TGFBR2TGFB1I10182312421567 -
TGFBR2TGFB1I10383112421567 -
GIT2TGFB1I10383110330411 -
GIT2TGFB1I10977910330411 -
MAPK15TGFB1I11686716624805 -
MAPK15TGFB1I10383116624805 -
TRAF4TGFB1I10383112023963 -
TRAF4TGFB1I10391512023963 -
HIPK3TGFB1I10511115231748 -
HIPK3TGFB1I10383115231748 -
UBQLN4TGFB1I10383116713569 -
UBQLN4TGFB1I10567016713569 -
GIT1TGFB1I10657712153727 -
GIT1TGFB1I10383112153727 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102784
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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