Gene Symbol:	TSPO ( BPBS,BZRP,DBI,IBP,MBR,PBR,PBS,PKBS,PTBR,mDRC,pk18 )
Gene Full Name:	translocator protein (18kDa)
Band:	22q13.2
Quick Links	Entrez ID:706; OMIM: 109610; Uniprot ID:TSPOA_HUMAN; ENSEMBL ID: ENSG00000100300; HGNC ID: 1158
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005741	TAS	-	mitochondrial outer membrane	-
GO:0016021	IEA	-	integral component of membrane	-
GO:0070062	IDA	-	extracellular exosome	19056867

GO ID	Evidence	Qualifier	GO_term	References
GO:0005497	IEA	-	androgen binding	-
GO:0005515	IPI	-	protein binding	25416956
GO:0008503	IEA	-	benzodiazepine receptor activity	-
GO:0015485	TAS	-	cholesterol binding	16822554
GO:0017127	TAS	-	cholesterol transporter activity	-
GO:0044325	IEA	-	ion channel binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006626	TAS	-	protein targeting to mitochondrion	1326278
GO:0006700	TAS	-	C21-steroid hormone biosynthetic process	-
GO:0006783	TAS	-	heme biosynthetic process	16822554
GO:0006820	TAS	-	anion transport	16822554
GO:0006821	IEA	-	chloride transport	-
GO:0006915	TAS	-	apoptotic process	16822554
GO:0007165	IEA	-	signal transduction	-
GO:0007568	IEA	-	aging	-
GO:0008202	TAS	-	steroid metabolic process	16822554
GO:0008283	TAS	-	cell proliferation	16822554
GO:0008347	IEA	-	glial cell migration	-
GO:0010042	IEA	-	response to manganese ion	-
GO:0010266	IEA	-	response to vitamin B1	-
GO:0010940	IEA	-	positive regulation of necrotic cell death	-
GO:0014012	IEA	-	peripheral nervous system axon regeneration	-
GO:0030301	IEA	-	cholesterol transport	-
GO:0030325	IEA	-	adrenal gland development	-
GO:0031397	IEA	-	negative regulation of protein ubiquitination	-
GO:0032374	TAS	-	regulation of cholesterol transport	16822554
GO:0032570	IEA	-	response to progesterone	-
GO:0032720	IEA	-	negative regulation of tumor necrosis factor production	-
GO:0033574	IEA	-	response to testosterone	-
GO:0042493	IEA	-	response to drug	-
GO:0043065	IEA	-	positive regulation of apoptotic process	-
GO:0045019	IEA	-	negative regulation of nitric oxide biosynthetic process	-
GO:0048266	IEA	-	behavioral response to pain	-
GO:0050810	IEA	-	regulation of steroid biosynthetic process	-
GO:0051901	IEA	-	positive regulation of mitochondrial depolarization	-
GO:0051928	IEA	-	positive regulation of calcium ion transport	-
GO:0060242	IEA	-	contact inhibition	-
GO:0060252	IEA	-	positive regulation of glial cell proliferation	-
GO:0060253	IEA	-	negative regulation of glial cell proliferation	-
GO:0071222	IEA	-	cellular response to lipopolysaccharide	-
GO:0071294	IEA	-	cellular response to zinc ion	-
GO:0071476	IEA	-	cellular hypotonic response	-
GO:0072656	IEA	-	maintenance of protein location in mitochondrion	-
GO:1903147	IEA	-	negative regulation of mitophagy	-
GO:1903579	IEA	-	negative regulation of ATP metabolic process	-
GO:2000379	IEA	-	positive regulation of reactive oxygen species metabolic process	-

Gene Symbol	Interactant	Interaction ID	References	Description
BZRAP1	TSPO	114680	9915832	Reconstituted Complex; Two-hybrid
BZRAP1	TSPO	107168	9915832	Reconstituted Complex; Two-hybrid

AutismKB 2.0

Annotation Details for TSPO