AutismKB 2.0

Annotation Details for TJP1


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Basic Information Top
Gene Symbol:TJP1 ( DKFZp686M05161,MGC133289,ZO-1 )
Gene Full Name: tight junction protein 1 (zona occludens 1)
Band: 15q13.1
Quick LinksEntrez ID:7082; OMIM: 601009; Uniprot ID:ZO1_HUMAN; ENSEMBL ID: ENSG00000104067; HGNC ID: 11827
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11734628
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005913TAS-cell-cell adherens junction8486731
GO:0005921IEA-gap junction-
GO:0005923IDA-bicellular tight junction11734628
GO:0016323IDA-basolateral plasma membrane16427635
GO:0030054IDA-cell junction28169360
GO:0043296IDA-apical junction complex16427635
GO:0045177IDA-apical part of cell22006950
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9707407
GO:0005516IEA-calmodulin binding-
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0007043TAS-cell-cell junction assembly8486731
GO:0035329TAS-hippo signaling-
GO:0090557IMP-establishment of endothelial intestinal barrier23885123
GO:1901350NAS-cell-cell signaling involved in cell-cell junction organization8395056
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TJP1CLDN410775610601346 Reconstituted Complex
TJP1CLDN411293710601346 Reconstituted Complex
TJP1CLDN310775710601346 Reconstituted Complex
TJP1CLDN311293710601346 Reconstituted Complex
TJP1CLDN710775810601346 Reconstituted Complex
TJP1CLDN711293710601346 Reconstituted Complex
TJP1EGFR11293712708492 Affinity Capture-Western
TJP1EGFR10827612708492 Affinity Capture-Western
TJP1GJA11089649707407 Affinity Capture-Western; Two-hybrid
TJP1GJA11129379707407 Affinity Capture-Western; Two-hybrid
TJP1GJA310896712808044 Affinity Capture-Western; Reconstituted Complex
TJP1GJA311293712808044 Affinity Capture-Western; Reconstituted Complex
TJP1GJA810897012808044 Affinity Capture-Western; Reconstituted Complex
TJP1GJA811293712808044 Affinity Capture-Western; Reconstituted Complex
TJP1HSP90AA111293718591668 Reconstituted Complex
TJP1HSP90AA110955218591668 Reconstituted Complex
TJP1MLLT411293710334923 Affinity Capture-Western; Reconstituted Complex
TJP1MLLT411044710334923 Affinity Capture-Western; Reconstituted Complex
TJP1NPHS111092815331416 Reconstituted Complex
TJP1NPHS111293715331416 Reconstituted Complex
TJP1PTPN1411174812808048 Affinity Capture-MS
TJP1PTPN1411293712808048 Affinity Capture-MS
LOC100506658TJP11110049792688 12169098 Affinity Capture-Western; Reconstituted Complex
LOC100506658TJP11129379792688 12169098 Affinity Capture-Western; Reconstituted Complex
TJP2TJP11148099792688 10026224 10575001 Affinity Capture-Western; Reconstituted Complex
TJP2TJP11129379792688 10026224 10575001 Affinity Capture-Western; Reconstituted Complex
TJP3TJP111802510575001 Affinity Capture-Western
TJP3TJP111293710575001 Affinity Capture-Western
CLDN5TJP111293710601346 Reconstituted Complex
CLDN5TJP111297710601346 Reconstituted Complex
CLDN8TJP111453010601346 Reconstituted Complex
CLDN8TJP111293710601346 Reconstituted Complex
CLDN6TJP111453110601346 Reconstituted Complex
CLDN6TJP111293710601346 Reconstituted Complex
CLDN2TJP111453210601346 Reconstituted Complex
CLDN2TJP111293710601346 Reconstituted Complex
CLDN1TJP111453310601346 Reconstituted Complex
CLDN1TJP111293710601346 Reconstituted Complex
F11RTJP111915310856295 12953056 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
F11RTJP111293710856295 12953056 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CGNTJP112158911042084 Reconstituted Complex
CGNTJP111293711042084 Reconstituted Complex
GJD3TJP112591512154091 Affinity Capture-Western; Reconstituted Complex
GJD3TJP111293712154091 Affinity Capture-Western; Reconstituted Complex
KIRRELTJP112053412578837 12865409 Affinity Capture-Western; Reconstituted Complex
KIRRELTJP111293712578837 12865409 Affinity Capture-Western; Reconstituted Complex
RAB8BTJP111293712639940 Affinity Capture-Western
RAB8BTJP111971912639940 Affinity Capture-Western
JAM2TJP111293712953056 Reconstituted Complex
JAM2TJP112182412953056 Reconstituted Complex
JAM3TJP111293712953056 Reconstituted Complex
JAM3TJP112373412953056 Reconstituted Complex
CSDATJP111410116508013 Reconstituted Complex
CSDATJP111293716508013 Reconstituted Complex
RAE1TJP111293719615732 Affinity Capture-MS
RAE1TJP111405419615732 Affinity Capture-MS
KBTBD7TJP112387320562859 Affinity Capture-MS
KBTBD7TJP111293720562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98759
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031001-2'