AutismKB 2.0

Annotation Details for TLE2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TLE2 ( ESG,ESG2,FLJ41188,GRG2 )
Gene Full Name: transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
Band: 19p13.3
Quick LinksEntrez ID:7089; OMIM: 601041; Uniprot ID:TLE2_HUMAN; ENSEMBL ID: ENSG00000065717; HGNC ID: 11838
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space22664934
GO:0005634IDA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005925IDA-focal adhesion-
GO:0016604IDA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0003714IDA-transcription corepressor activity19460168
GO:0005515IPI-protein binding17041588
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0007165TAS-signal transduction8808280
GO:0009887TAS-animal organ morphogenesis8808280
GO:0016055IEA-Wnt signaling pathway-
GO:0045892IDA-negative regulation of transcription, DNA-templated19460168
GO:0090090IDA-negative regulation of canonical Wnt signaling pathway19460168
GO:1904837TAS-beta-catenin-TCF complex assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TLE2PRDM11129449887105 Reconstituted Complex
TLE2PRDM11071089887105 Reconstituted Complex
TLE2EMX211294420211142 Two-hybrid
TLE2EMX210833320211142 Two-hybrid
TLE2FOXA311294420211142 Two-hybrid
TLE2FOXA310941320211142 Two-hybrid
TLE2HES11129449874198 Reconstituted Complex; Two-hybrid
TLE2HES11095149874198 Reconstituted Complex; Two-hybrid
TLE2MSX111294420211142 Two-hybrid
TLE2MSX111059320211142 Two-hybrid
TLE2MSX211294420211142 Two-hybrid
TLE2MSX211059420211142 Two-hybrid
TLE2PAX911111720211142 Two-hybrid
TLE2PAX911294420211142 Two-hybrid
TLE2TLE11129439874198 Reconstituted Complex; Two-hybrid
TLE2TLE11129449874198 Reconstituted Complex; Two-hybrid
UTYTLE21129449854018 Two-hybrid
UTYTLE21132479854018 Two-hybrid
TLE2TLE21129449874198 Reconstituted Complex
CUL4BTLE211402817041588 Affinity Capture-MS; Affinity Capture-Western
CUL4BTLE211294417041588 Affinity Capture-MS; Affinity Capture-Western
CUL4ATLE211402917041588 Affinity Capture-Western
CUL4ATLE211294417041588 Affinity Capture-Western
VENTXTLE211294420211142 Two-hybrid
VENTXTLE211811120211142 Two-hybrid
TLX3TLE211294420211142 Two-hybrid
TLX3TLE211903020211142 Two-hybrid
BARHL1TLE212119520211142 Two-hybrid
BARHL1TLE211294420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104635
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2826'