AutismKB 2.0

Annotation Details for TLR5


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Basic Information Top
Gene Symbol:TLR5 ( FLJ10052,MGC126430,MGC126431,SLEB1,TIL3 )
Gene Full Name: toll-like receptor 5
Band: 1q41
Quick LinksEntrez ID:7100; OMIM: 603031; Uniprot ID:TLR5_HUMAN; ENSEMBL ID: ENSG00000187554; HGNC ID: 11851
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0004888IEA-transmembrane signaling receptor activity-
GO:0005149IPI-interleukin-1 receptor binding12925853
GO ID Evidence Qualifier GO_term References
GO:0002755TAS-MyD88-dependent toll-like receptor signaling pathway-
GO:0006954IEA-inflammatory response-
GO:0008584IEA-male gonad development-
GO:0032757IDA-positive regulation of interleukin-8 production17128265
GO:0034123IDA-positive regulation of toll-like receptor signaling pathway17128265
GO:0034146TAS-toll-like receptor 5 signaling pathway-
GO:0042742IEA-defense response to bacterium-
GO:0045087IEA-innate immune response-
GO:0045429IEA-positive regulation of nitric oxide biosynthetic process-
GO:0050707IEA-regulation of cytokine secretion-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071260IEP-cellular response to mechanical stimulus19593445
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TLR5MYD8811295515107846 Two-hybrid
TLR5MYD8811070015107846 Two-hybrid
RNF216TLR511295515107846 Two-hybrid
RNF216TLR511998115107846 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1858171
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040219-14'