AutismKB 2.0

Annotation Details for CLDN5


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Basic Information Top
Gene Symbol:CLDN5 ( AWAL,BEC1,CPETRL1,TMVCF )
Gene Full Name: claudin 5
Band: 22q11.21
Quick LinksEntrez ID:7122; OMIM: 602101; Uniprot ID:CLD5_HUMAN; ENSEMBL ID: ENSG00000184113; HGNC ID: 2047
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane25978380
GO:0005911IDA-cell-cell junction18065521
GO:0005923IDA-bicellular tight junction9892664
GO:0005923ISS-bicellular tight junction-
GO:0016021NAS-integral component of membrane9892664
GO:0016021TAS-integral component of membrane9192844
GO:0016327IDA-apicolateral plasma membrane9892664
GO:0030864IDAcolocalizes_withcortical actin cytoskeleton25816133
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005198IEA-structural molecule activity-
GO:0042802ISS-identical protein binding-
GO ID Evidence Qualifier GO_term References
GO:0003151TAS-outflow tract morphogenesis9192844
GO:0007043IMP-cell-cell junction assembly23288152
GO:0007179IDA-transforming growth factor beta receptor signaling pathway21168935
GO:0007612TAS-learning9192844
GO:0016338ISS-calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules-
GO:0060021TAS-palate development9192844
GO:0060325TAS-face morphogenesis9192844
GO:1903142IMP-positive regulation of establishment of endothelial barrier23288152
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CLDN5CLDN310775712909588 Affinity Capture-Western
CLDN5CLDN311297712909588 Affinity Capture-Western
CLDN5TJP111293710601346 Reconstituted Complex
CLDN5TJP111297710601346 Reconstituted Complex
CLDN1CLDN511453312909588 Affinity Capture-Western
CLDN1CLDN511297712909588 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
CLDN5CLDN5_844, CLDN5_V1, rs10314, rs1548359, rs739371 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1276112
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2442'