AutismKB 2.0

Annotation Details for TNNT2


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Basic Information Top
Gene Symbol:TNNT2 ( CMH2,CMPD2,LVNC6,MGC3889,RCM3,TnTC,cTnT )
Gene Full Name: troponin T type 2 (cardiac)
Band: 1q32.1
Quick LinksEntrez ID:7139; OMIM: 191045; Uniprot ID:TNNT2_HUMAN; ENSEMBL ID: ENSG00000118194; HGNC ID: 11949
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005861IDA-troponin complex12186860
GO:0005865IDA-striated muscle thin filament12186860
GO:0030017TAS-sarcomere16754800
GO:0097512IDA-cardiac myofibril25771144
GO:1990584IDA-cardiac Troponin complex25771144
GO ID Evidence Qualifier GO_term References
GO:0003779IDA-actin binding8205619
GO:0005515IPI-protein binding25416956
GO:0005523IDA-tropomyosin binding10850966
GO:0030172IPI-troponin C binding8205619
GO:0030674IEA-protein binding, bridging-
GO:0031013IPI-troponin I binding15542288
GO ID Evidence Qualifier GO_term References
GO:0008016IMP-regulation of heart contraction15542288
GO:0030049IDA-muscle filament sliding12186860
GO:0030049TAS-muscle filament sliding-
GO:0032780IDA-negative regulation of ATPase activity10850966
GO:0032781IDA-positive regulation of ATPase activity10850966
GO:0032972IEA-regulation of muscle filament sliding speed-
GO:0051291IEA-protein heterooligomerization-
GO:0051592IMP-response to calcium ion8205619
GO:0051764IEA-actin crosslink formation-
GO:0055010IMP-ventricular cardiac muscle tissue morphogenesis16754800
GO:0060048IDA-cardiac muscle contraction25771144
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNNT2TNNI311299111904166 Reconstituted Complex
TNNT2TNNI311299311904166 Reconstituted Complex
TPM1TNNT21129936746613 Reconstituted Complex
TPM1TNNT21130216746613 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104597
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000626-1'