AutismKB 2.0

Annotation Details for TPH1


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Basic Information Top
Gene Symbol:TPH1 ( MGC119994,TPRH,TRPH )
Gene Full Name: tryptophan hydroxylase 1
Band: 11p15.1
Quick LinksEntrez ID:7166; OMIM: 191060; Uniprot ID:TPH1_HUMAN; ENSEMBL ID: ENSG00000129167; HGNC ID: 12008
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0043005IEA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0004510IEA-tryptophan 5-monooxygenase activity-
GO:0005506IEA-iron ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007623IEA-circadian rhythm-
GO:0009072IEA-aromatic amino acid family metabolic process-
GO:0030279IEA-negative regulation of ossification-
GO:0035902IEA-response to immobilization stress-
GO:0042427IEA-serotonin biosynthetic process-
GO:0045600IEA-positive regulation of fat cell differentiation-
GO:0046219TAS-indolalkylamine biosynthetic process-
GO:0046849IEA-bone remodeling-
GO:0055114IEA-oxidation-reduction process-
GO:0060749IEA-mammary gland alveolus development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
YWHAZTPH11133668101440 Reconstituted Complex
YWHAZTPH11130198101440 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
TPH1rs211103 Gene overview in AlzGene
No data
Gene Symbol Poly Names Gene overview in SZGene
TPH1TPH1_-6526A/G, TPH1_-7065C/T, TPH1_-7180G/T, TPH1_5pb-Indel, TPH1_IVS7nt13, TPH1_SNP, rs10488683, rs10741734, rs1799913, rs1800532, rs211102, rs211105, rs4537731, rs684302, rs7933505, rs9633898 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:98796
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030317-1'