AutismKB 2.0

Annotation Details for TRAF1


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Basic Information Top
Gene Symbol:TRAF1 ( EBI6,MGC:10353 )
Gene Full Name: TNF receptor-associated factor 1
Band: 9q33.2
Quick LinksEntrez ID:7185; OMIM: 601711; Uniprot ID:TRAF1_HUMAN; ENSEMBL ID: ENSG00000056558; HGNC ID: 12031
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm8069916
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005164IPI-tumor necrosis factor receptor binding11728344
GO:0005515IPI-protein binding8069916
GO:0008270IEA-zinc ion binding-
GO:0031625IPI-ubiquitin protein ligase binding11279055
GO:0031996IPI-thioesterase binding11279055
GO:0042802IPI-identical protein binding8069916
GO ID Evidence Qualifier GO_term References
GO:0006461TAS-protein complex assembly8069916
GO:0006915IEA-apoptotic process-
GO:0007165IEA-signal transduction-
GO:0010803TAS-regulation of tumor necrosis factor-mediated signaling pathway-
GO:0051092IDA-positive regulation of NF-kappaB transcription factor activity10692572
GO:2001236IDA-regulation of extrinsic apoptotic signaling pathway10692572
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRAF1BIRC21068268943045 9384571 11907583 Affinity Capture-Western; Reconstituted Complex
TRAF1BIRC21130378943045 9384571 11907583 Affinity Capture-Western; Reconstituted Complex
TRAF1BIRC31068279384571 11907583 Reconstituted Complex
TRAF1BIRC31130379384571 11907583 Reconstituted Complex
TRAF1TNFRSF1710708010903733 Affinity Capture-Western
TRAF1TNFRSF1711303710903733 Affinity Capture-Western
TRAF1CASP610728911098060 Biochemical Activity
TRAF1CASP611303711098060 Biochemical Activity
TRAF1CASP810729111098060 12887920 Affinity Capture-Western; Biochemical Activity
TRAF1CASP811303711098060 12887920 Affinity Capture-Western; Biochemical Activity
TRAF1CASP1011303711098060 Biochemical Activity
TRAF1CASP1010729311098060 Biochemical Activity
TRAF1CD271073779794406 Affinity Capture-Western
TRAF1CD271130379794406 Affinity Capture-Western
TRAF1TNFRSF91098179464265 Reconstituted Complex
TRAF1TNFRSF91130379464265 Reconstituted Complex
TRAF1LTBR1130379162022 Reconstituted Complex
TRAF1LTBR1102339162022 Reconstituted Complex
TRAF1MAP3K51130379774977 Affinity Capture-Western
TRAF1MAP3K51103819774977 Affinity Capture-Western
TRAF1TRIM3711303711279055 Reconstituted Complex
TRAF1TRIM3711067811279055 Reconstituted Complex
TRAF1NGFR11087010514511 Affinity Capture-Western
TRAF1NGFR11303710514511 Affinity Capture-Western
TRAF1SUMO211303719394292 Affinity Capture-MS
TRAF1SUMO211249719394292 Affinity Capture-MS
TRAF1SRC11259210635328 Affinity Capture-Western
TRAF1SRC11303710635328 Affinity Capture-Western
TRAF1TNFAIP31130378692885 9928991 Affinity Capture-Western; Two-hybrid
TRAF1TNFAIP31129838692885 9928991 Affinity Capture-Western; Two-hybrid
TRAF1TNFRSF1A1129868565075 Affinity Capture-Western
TRAF1TNFRSF1A1130378565075 Affinity Capture-Western
TRAF1TNFRSF1B1129879162022 Reconstituted Complex
TRAF1TNFRSF1B1130379162022 Reconstituted Complex
TRADDTRAF11142578565075 Affinity Capture-Western
TRADDTRAF11130378565075 Affinity Capture-Western
RIPK1TRAF11142748612133 Affinity Capture-Western
RIPK1TRAF11130378612133 Affinity Capture-Western
TRAF2TRAF11130378702708 14743216 Affinity Capture-MS; Affinity Capture-Western
TRAF2TRAF11130388702708 14743216 Affinity Capture-MS; Affinity Capture-Western
TANKTRAF11130378710854 Two-hybrid
TANKTRAF11153288710854 Two-hybrid
TRAIPTRAF11130379104814 Reconstituted Complex; Two-hybrid
TRAIPTRAF11155819104814 Reconstituted Complex; Two-hybrid
TNFRSF14TRAF11142989162022 Reconstituted Complex
TNFRSF14TRAF11130379162022 Reconstituted Complex
CFLARTRAF11143649208847 10837247 Affinity Capture-Western
CFLARTRAF11130379208847 10837247 Affinity Capture-Western
TNFSF9TRAF11142819607925 Affinity Capture-Western; Reconstituted Complex
TNFSF9TRAF11130379607925 Affinity Capture-Western; Reconstituted Complex
RIPK2TRAF11130379705938 Affinity Capture-Western
RIPK2TRAF11143009705938 Affinity Capture-Western
TNFRSF11ATRAF11143209852070 10025951 Affinity Capture-Western; Reconstituted Complex
TNFRSF11ATRAF11130379852070 10025951 Affinity Capture-Western; Reconstituted Complex
TNFRSF18TRAF111431210037686 Affinity Capture-Western
TNFRSF18TRAF111303710037686 Affinity Capture-Western
MAP3K14TRAF111303711278268 Reconstituted Complex
MAP3K14TRAF111448711278268 Reconstituted Complex
USP7TRAF111362211279055 Reconstituted Complex
USP7TRAF111303711279055 Reconstituted Complex
SPOPTRAF111399311279055 Reconstituted Complex
SPOPTRAF111303711279055 Reconstituted Complex
TNFRSF12ATRAF111947811728344 Reconstituted Complex
TNFRSF12ATRAF111303711728344 Reconstituted Complex
HIVEP3TRAF111303711804591 Affinity Capture-Western; Two-hybrid
HIVEP3TRAF112186111804591 Affinity Capture-Western; Two-hybrid
UBCTRAF111316415468071 Affinity Capture-Western
UBCTRAF111303715468071 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101836
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-071120-4'