Annotation Details for TRAF2


Gene Symbol: | TRAF2 ( MGC:45012,TRAP,TRAP3 ) |
---|---|
Gene Full Name: | TNF receptor-associated factor 2 |
Band: | 9q34.3 |
Quick Links | Entrez ID:7186; OMIM: 601895; Uniprot ID:TRAF2_HUMAN; ENSEMBL ID: ENSG00000127191; HGNC ID: 12032 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000151 | IPI | - | ubiquitin ligase complex | 17314283 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005829 | IDA | - | cytosol | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0005938 | IEA | - | cell cortex | - |
GO:0009898 | ISS | - | cytoplasmic side of plasma membrane | - |
GO:0012506 | IEA | - | vesicle membrane | - |
GO:0035631 | ISS | - | CD40 receptor complex | - |
GO:0045121 | IEA | - | membrane raft | - |
GO:0097057 | IDA | - | TRAF2-GSTP1 complex | 16636664 |
GO:1990597 | IEA | - | AIP1-IRE1 complex | - |
GO:1990604 | IDA | - | IRE1-TRAF2-ASK1 complex | 23000344 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004842 | IDA | - | ubiquitin-protein transferase activity | 15258597 |
GO:0004871 | NAS | - | signal transducer activity | 8702708 |
GO:0005164 | IPI | - | tumor necrosis factor receptor binding | 11279055 |
GO:0005174 | ISS | - | CD40 receptor binding | - |
GO:0005515 | IPI | - | protein binding | 8069916 |
GO:0008270 | IEA | - | zinc ion binding | - |
GO:0019899 | IPI | - | enzyme binding | 16636664 |
GO:0019901 | IPI | - | protein kinase binding | 10650002 |
GO:0019903 | IPI | - | protein phosphatase binding | 15696169 |
GO:0031435 | IEA | - | mitogen-activated protein kinase kinase kinase binding | - |
GO:0031625 | IPI | - | ubiquitin protein ligase binding | 11279055 |
GO:0031996 | IPI | - | thioesterase binding | 11279055 |
GO:0032403 | IEA | - | protein complex binding | - |
GO:0042802 | IPI | - | identical protein binding | 8069916 |
GO:0046625 | IDA | - | sphingolipid binding | 20577214 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0002726 | IMP | - | positive regulation of T cell cytokine production | 15125833 |
GO:0006461 | TAS | - | protein complex assembly | 8702708 |
GO:0006919 | TAS | - | activation of cysteine-type endopeptidase activity involved in apoptotic process | - |
GO:0007165 | TAS | - | signal transduction | 8702708 |
GO:0007249 | TAS | - | I-kappaB kinase/NF-kappaB signaling | - |
GO:0007250 | IMP | - | activation of NF-kappaB-inducing kinase activity | 15125833 |
GO:0010803 | TAS | - | regulation of tumor necrosis factor-mediated signaling pathway | - |
GO:0016579 | TAS | - | protein deubiquitination | - |
GO:0030163 | IEA | - | protein catabolic process | - |
GO:0032743 | IMP | - | positive regulation of interleukin-2 production | 15125833 |
GO:0033209 | IDA | - | tumor necrosis factor-mediated signaling pathway | 11907583 |
GO:0033209 | TAS | - | tumor necrosis factor-mediated signaling pathway | - |
GO:0034351 | IEA | - | negative regulation of glial cell apoptotic process | - |
GO:0034976 | NAS | - | response to endoplasmic reticulum stress | 10650002 |
GO:0042981 | IDA | - | regulation of apoptotic process | 11907583 |
GO:0043507 | IDA | - | positive regulation of JUN kinase activity | 11907583 |
GO:0043623 | ISS | - | cellular protein complex assembly | - |
GO:0050870 | IC | - | positive regulation of T cell activation | 15125833 |
GO:0051023 | IEA | - | regulation of immunoglobulin secretion | - |
GO:0051091 | IMP | - | positive regulation of sequence-specific DNA binding transcription factor activity | 12296995 |
GO:0051092 | IDA | - | positive regulation of NF-kappaB transcription factor activity | 11279055 |
GO:0051092 | IMP | - | positive regulation of NF-kappaB transcription factor activity | 12296995 |
GO:0051291 | IEA | - | protein heterooligomerization | - |
GO:0051865 | IDA | - | protein autoubiquitination | 20577214 |
GO:0051865 | TAS | - | protein autoubiquitination | 16378096 |
GO:0060544 | TAS | - | regulation of necroptotic process | - |
GO:0070059 | TAS | - | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 14685163 |
GO:0070207 | IPI | - | protein homotrimerization | 20447407 |
GO:0070534 | IDA | - | protein K63-linked ubiquitination | 15258597 |
GO:0071550 | TAS | - | death-inducing signaling complex assembly | - |
GO:0071732 | IEA | - | cellular response to nitric oxide | - |
GO:0090073 | IMP | - | positive regulation of protein homodimerization activity | 11278723 |
GO:0097296 | TAS | - | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | - |
GO:0097300 | IEA | - | programmed necrotic cell death | - |
GO:1901215 | TAS | - | negative regulation of neuron death | 18221368 |
GO:1902041 | TAS | - | regulation of extrinsic apoptotic signaling pathway via death domain receptors | - |
GO:1902042 | TAS | - | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | - |
GO:1903265 | IEA | - | positive regulation of tumor necrosis factor-mediated signaling pathway | - |
GO:1903721 | IEA | - | positive regulation of I-kappaB phosphorylation | - |
GO:2001238 | IMP | - | positive regulation of extrinsic apoptotic signaling pathway | 21525013 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
TRAF2 | PTPN2 | 216135 | 15696169 | PTPN2 (TCPTP) interacts with TRAF2. |
No data |
Gene Symbol | Poly Names | Gene overview in AlzGene |
---|---|---|
TRAF2 | rs10747039, rs10781520, rs17250680, rs1800631, rs7852970 | Gene overview in AlzGene |
No data |
No data |
- MGI ID: MGI:101835
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-030131-5345