AutismKB 2.0

Annotation Details for TRIO


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Basic Information Top
Gene Symbol:TRIO ( ARHGEF23,FLJ42780,tgat )
Gene Full Name: triple functional domain (PTPRF interacting)
Band: 5p15.2
Quick LinksEntrez ID:7204; OMIM: 601893; Uniprot ID:TRIO_HUMAN; ENSEMBL ID: ENSG00000038382; HGNC ID: 12303
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004674IEA-protein serine/threonine kinase activity-
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding17043677
GO:0005524IEA-ATP binding-
GO:0019899IEA-enzyme binding-
GO ID Evidence Qualifier GO_term References
GO:0006468IEA-protein phosphorylation-
GO:0007185TAS-transmembrane receptor protein tyrosine phosphatase signaling pathway8643598
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRIORHOA11305510948190 Affinity Capture-Western; Co-localization; Reconstituted Complex
TRIORHOA10688010948190 Affinity Capture-Western; Co-localization; Reconstituted Complex
TRIOBLMH11305516169070 Two-hybrid
TRIOBLMH10711116169070 Two-hybrid
TRIOFLNA11305511146652 Reconstituted Complex; Two-hybrid
TRIOFLNA10860511146652 Reconstituted Complex; Two-hybrid
TRIOPTPRF1130558643598 Affinity Capture-Western
TRIOPTPRF1117568643598 Affinity Capture-Western
TRIORAC111305511595749 Reconstituted Complex
TRIORAC111181711595749 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927230
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030616-399'