AutismKB 2.0

Annotation Details for TRPC6


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Basic Information Top
Gene Symbol:TRPC6 ( FLJ11098,FLJ14863,FSGS2,TRP6 )
Gene Full Name: transient receptor potential cation channel, subfamily C, member 6
Band: 11q22.1
Quick LinksEntrez ID:7225; OMIM: 603652; Uniprot ID:TRPC6_HUMAN; ENSEMBL ID: ENSG00000137672; HGNC ID: 12338
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm23171048
GO:0005886IDA-plasma membrane10998353
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0016020IDA-membrane23171048
GO:0036057IEA-slit diaphragm-
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0005262TAS-calcium channel activity-
GO:0005515IPI-protein binding15757897
GO:0015279IBA-store-operated calcium channel activity-
GO:0030276IEA-clathrin binding-
GO:0042805IEA-actinin binding-
GO:0051117IEA-ATPase binding-
GO:0070679IDA-inositol 1,4,5 trisphosphate binding14505576
GO ID Evidence Qualifier GO_term References
GO:0006812TAS-cation transport9930701
GO:0006828IBA-manganese ion transport-
GO:0007204IEA-positive regulation of cytosolic calcium ion concentration-
GO:0007338IBA-single fertilization-
GO:0007568IEA-aging-
GO:0010800IEA-positive regulation of peptidyl-threonine phosphorylation-
GO:0030168TAS-platelet activation-
GO:0030182IEA-neuron differentiation-
GO:0032414IDA-positive regulation of ion transmembrane transporter activity10998353
GO:0045666IEA-positive regulation of neuron differentiation-
GO:0050774IEA-negative regulation of dendrite morphogenesis-
GO:0051480IBA-regulation of cytosolic calcium ion concentration-
GO:0051928IDA-positive regulation of calcium ion transport10998353
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0070588TAS-calcium ion transmembrane transport-
GO:0071456IEA-cellular response to hypoxia-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRPC6FYN10881014761972 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TRPC6FYN11307614761972 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TRPC6ITPR111307614505576 Affinity Capture-Western
TRPC6ITPR110991314505576 Affinity Capture-Western
TRPC6ITPR311307611290752 Reconstituted Complex
TRPC6ITPR310991511290752 Reconstituted Complex
TRPC6SRC11259214761972 Affinity Capture-Western
TRPC6SRC11307614761972 Affinity Capture-Western
TRPC6TRPC111307612857742 Affinity Capture-Western
TRPC6TRPC111307112857742 Affinity Capture-Western
TRPC6TRPC211307214699131 Affinity Capture-Western
TRPC6TRPC211307614699131 Affinity Capture-Western
TRPC6TRPC311307612032305 Affinity Capture-Western; FRET
TRPC6TRPC311307312032305 Affinity Capture-Western; FRET
TRPC6TRPC411307612857742 Affinity Capture-Western
TRPC6TRPC411307412857742 Affinity Capture-Western
TRPC6TRPC511307512857742 Affinity Capture-Western
TRPC6TRPC511307612857742 Affinity Capture-Western
TRPC6TRPC611307612032305 Affinity Capture-Western; FRET
TRPC7TRPC611307612032305 FRET
TRPC7TRPC612137812032305 FRET
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109523
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040724-114'