AutismKB 2.0

Annotation Details for TRPM2


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Basic Information Top
Gene Symbol:TRPM2 ( EREG1,KNP3,LTRPC2,MGC133383,NUDT9H,NUDT9L1,TRPC7 )
Gene Full Name: transient receptor potential cation channel, subfamily M, member 2
Band: 21q22.3
Quick LinksEntrez ID:7226; OMIM: 603749; Uniprot ID:TRPM2_HUMAN; ENSEMBL ID: ENSG00000142185; HGNC ID: 12339
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005764IDA-lysosome27068538
GO:0005765ISS-lysosomal membrane-
GO:0005886TAS-plasma membrane-
GO:0005887IMP-integral component of plasma membrane19171771
GO:0005887ISS-integral component of plasma membrane-
GO:0030659ISS-cytoplasmic vesicle membrane-
GO:0035579TAS-specific granule membrane-
GO:0042995IEA-cell projection-
GO:0043204IEA-perikaryon-
GO:0070821TAS-tertiary granule membrane-
GO:0101003TAS-ficolin-1-rich granule membrane-
GO ID Evidence Qualifier GO_term References
GO:0005261IMP-cation channel activity27068538
GO:0005262TAS-calcium channel activity-
GO:0005272IEA-sodium channel activity-
GO:0005509IMP-calcium ion binding19171771
GO:0015278IMP-calcium-release channel activity27068538
GO:0016787IMPNOThydrolase activity27383051
GO:0099604IDA-ligand-gated calcium channel activity19171771
GO ID Evidence Qualifier GO_term References
GO:0001659ISS-temperature homeostasis-
GO:0002407ISS-dendritic cell chemotaxis-
GO:0006816TAS-calcium ion transport9806837
GO:0014074IMP-response to purine-containing compound19171771
GO:0035584ISS-calcium-mediated signaling using intracellular calcium source-
GO:0035725IEA-sodium ion transmembrane transport-
GO:0043312TAS-neutrophil degranulation-
GO:0051209IMP-release of sequestered calcium ion into cytosol27068538
GO:0051209ISS-release of sequestered calcium ion into cytosol-
GO:0051489IMP-regulation of filopodium assembly27068538
GO:0070301IDA-cellular response to hydrogen peroxide27068538
GO:0070588TAS-calcium ion transmembrane transport-
GO:0071277IMP-cellular response to calcium ion19171771
GO:0071415ISS-cellular response to purine-containing compound-
GO:0071502ISS-cellular response to temperature stimulus-
GO:0071577IMP-zinc II ion transmembrane transport27068538
GO:0097028ISS-dendritic cell differentiation-
GO:0097553IMP-calcium ion transmembrane import into cytosol19171771
GO:0098703ISS-calcium ion import across plasma membrane-
GO:2000249IMP-regulation of actin cytoskeleton reorganization27068538
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1351901
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061214-4'