AutismKB 2.0

Annotation Details for HIRA


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Basic Information Top
Gene Symbol:HIRA ( DGCR1,TUP1,TUPLE1 )
Gene Full Name: HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
Band: 22q11.21
Quick LinksEntrez ID:7290; OMIM: 600237; Uniprot ID:HIRA_HUMAN; ENSEMBL ID: ENSG00000100084,ENSG00000242259; HGNC ID: 4916
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin14718166
GO:0005634IDA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0016605IEA-PML body-
GO:0043234IDA-protein complex14718166
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9731536
GO:0003714TAS-transcription corepressor activity9731536
GO:0005515IPI-protein binding9710638
GO:0031491IBA-nucleosome binding-
GO ID Evidence Qualifier GO_term References
GO:0001649IEA-osteoblast differentiation-
GO:0006336IDA-DNA replication-independent nucleosome assembly14718166
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9731536
GO:0007369IEA-gastrulation-
GO:0009653TAS-anatomical structure morphogenesis7633437
GO:0016569IEA-covalent chromatin modification-
GO:0031935IBA-regulation of chromatin silencing-
GO:0042692IEA-muscle cell differentiation-
GO:1903507IEA-negative regulation of nucleic acid-templated transcription-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HIRAHIST1H2BD1131419710638 Two-hybrid
HIRAHIST1H2BD1092709710638 Two-hybrid
HIRAH3F3A11314114718166 20211137 Affinity Capture-MS; Affinity Capture-Western; Co-localization
HIRAH3F3A10927214718166 20211137 Affinity Capture-MS; Affinity Capture-Western; Co-localization
HIRAMEF2D11037321414300 Affinity Capture-Western
HIRAMEF2D11314121414300 Affinity Capture-Western
HIRAUPF111190815231747 Two-hybrid
HIRAUPF111314115231747 Two-hybrid
HIRIP3HIRA1140539710638 Reconstituted Complex
HIRIP3HIRA1131419710638 Reconstituted Complex
HIST1H2BKHIRA1244399710638 Reconstituted Complex; Two-hybrid
HIST1H2BKHIRA1131419710638 Reconstituted Complex; Two-hybrid
NFU1HIRA11809511342215 Reconstituted Complex; Two-hybrid
NFU1HIRA11314111342215 Reconstituted Complex; Two-hybrid
ASF1AHIRA11736815621527 16980972 18378699 21414300 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
ASF1AHIRA11314115621527 16980972 18378699 21414300 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
ASF1BHIRA12084516980972 Affinity Capture-Western; Reconstituted Complex
ASF1BHIRA11314116980972 Affinity Capture-Western; Reconstituted Complex
CABIN1HIRA11707021414300 Affinity Capture-Western
CABIN1HIRA11314121414300 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
HIRACCNA21317611238922 HIRA interacts with Cyclin A
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
HIRAD22S941, HIRA*SC16285355, HIRA*SC16311183, HIRA*SC16322982 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99430
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6296'