Gene Symbol:	TYRO3 ( BYK,Dtk,FLJ16467,RSE,Sky,Tif )
Gene Full Name:	TYRO3 protein tyrosine kinase
Band:	15q15.1
Quick Links	Entrez ID:7301; OMIM: 600341; Uniprot ID:TYRO3_HUMAN; ENSEMBL ID: ENSG00000092445; HGNC ID: 12446
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	ISS	-	nucleus	-
GO:0005635	ISS	-	nuclear envelope	-
GO:0005789	ISS	-	endoplasmic reticulum membrane	-
GO:0005887	NAS	-	integral component of plasma membrane	7511603

GO ID	Evidence	Qualifier	GO_term	References
GO:0001618	IEA	-	virus receptor activity	-
GO:0004713	IDA	-	protein tyrosine kinase activity	7537495
GO:0004714	NAS	-	transmembrane receptor protein tyrosine kinase activity	7511603
GO:0004716	NAS	-	signal transducer, downstream of receptor, with protein tyrosine kinase activity	7511603
GO:0005515	IPI	-	protein binding	7634325
GO:0005524	IEA	-	ATP binding	-
GO:0043548	IPI	-	phosphatidylinositol 3-kinase binding	10627473
GO:0046982	IEA	-	protein heterodimerization activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001779	IEA	-	natural killer cell differentiation	-
GO:0007155	NAS	-	cell adhesion	8108112
GO:0007165	NAS	-	signal transduction	7511603
GO:0007283	ISS	-	spermatogenesis	-
GO:0014065	NAS	-	phosphatidylinositol 3-kinase signaling	10627473
GO:0018108	IEA	-	peptidyl-tyrosine phosphorylation	-
GO:0021885	ISS	-	forebrain cell migration	-
GO:0023014	IEA	-	signal transduction by protein phosphorylation	-
GO:0030168	ISS	-	platelet activation	-
GO:0032940	ISS	-	secretion by cell	-
GO:0034122	ISS	-	negative regulation of toll-like receptor signaling pathway	-
GO:0034446	ISS	-	substrate adhesion-dependent cell spreading	-
GO:0042698	ISS	-	ovulation cycle	-
GO:0043277	ISS	-	apoptotic cell clearance	-
GO:0043491	ISS	-	protein kinase B signaling	-
GO:0043524	ISS	-	negative regulation of neuron apoptotic process	-
GO:0045824	ISS	-	negative regulation of innate immune response	-
GO:0046718	IEA	-	viral entry into host cell	-
GO:0046777	IDA	-	protein autophosphorylation	7511603
GO:0050728	ISS	-	negative regulation of inflammatory response	-
GO:0051250	IEA	-	negative regulation of lymphocyte activation	-
GO:0060068	IEA	-	vagina development	-
GO:0070050	ISS	-	neuron cellular homeostasis	-
GO:0070527	ISS	-	platelet aggregation	-

Gene Symbol	Interactant	Interaction ID	References	Description
TYRO3	GAS6	108891	8621659 8939948	Reconstituted Complex
TYRO3	GAS6	113152	8621659 8939948	Reconstituted Complex
TYRO3	PIK3R1	113152	10627473	Affinity Capture-Western; Two-hybrid
TYRO3	PIK3R1	111313	10627473	Affinity Capture-Western; Two-hybrid
TYRO3	SRC	112592	7537495	Affinity Capture-Western
TYRO3	SRC	113152	7537495	Affinity Capture-Western
IKBKG	TYRO3	114089	20098747	Reconstituted Complex
IKBKG	TYRO3	113152	20098747	Reconstituted Complex

AutismKB 2.0

Annotation Details for TYRO3