AutismKB 2.0

Annotation Details for UBA52


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Basic Information Top
Gene Symbol:UBA52 ( CEP52,HUBCEP52,MGC126879,MGC126881,MGC57125,RPL40 )
Gene Full Name: ubiquitin A-52 residue ribosomal protein fusion product 1
Band: 19p13.1-p12
Quick LinksEntrez ID:7311; OMIM: 191321; Uniprot ID:RL40_HUMAN; ENSEMBL ID: ENSG00000221983; HGNC ID: 12458
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space16502470
GO:0005634IDA-nucleus21630459
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005741TAS-mitochondrial outer membrane-
GO:0005765IDA-lysosomal membrane17897319
GO:0005783IDA-endoplasmic reticulum-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0010008TAS-endosome membrane-
GO:0022625IEA-cytosolic large ribosomal subunit-
GO:0030666TAS-endocytic vesicle membrane-
GO:0031982IDA-vesicle19190083
GO:0043209IEA-myelin sheath-
GO:0044322IEA-endoplasmic reticulum quality control compartment-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0003735IEA-structural constituent of ribosome-
GO:0005515IPI-protein binding15147878
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter-
GO:0000165TAS-MAPK cascade-
GO:0000184TAS-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-
GO:0000187TAS-activation of MAPK activity-
GO:0000209TAS-protein polyubiquitination-
GO:0000715TAS-nucleotide-excision repair, DNA damage recognition-
GO:0000717TAS-nucleotide-excision repair, DNA duplex unwinding-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002755TAS-MyD88-dependent toll-like receptor signaling pathway-
GO:0002756TAS-MyD88-independent toll-like receptor signaling pathway-
GO:0005978TAS-glycogen biosynthetic process-
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006294TAS-nucleotide-excision repair, preincision complex assembly-
GO:0006296TAS-nucleotide-excision repair, DNA incision, 5'-to lesion-
GO:0006297TAS-nucleotide-excision repair, DNA gap filling-
GO:0006364TAS-rRNA processing-
GO:0006413TAS-translational initiation-
GO:0006457TAS-protein folding-
GO:0006464TAS-cellular protein modification process2581967
GO:0006614TAS-SRP-dependent cotranslational protein targeting to membrane-
GO:0006879TAS-cellular iron ion homeostasis-
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0007179TAS-transforming growth factor beta receptor signaling pathway-
GO:0007219TAS-Notch signaling pathway-
GO:0007249TAS-I-kappaB kinase/NF-kappaB signaling-
GO:0007254TAS-JNK cascade-
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0010803TAS-regulation of tumor necrosis factor-mediated signaling pathway-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016055TAS-Wnt signaling pathway-
GO:0016197TAS-endosomal transport-
GO:0016236TAS-macroautophagy-
GO:0016567TAS-protein ubiquitination-
GO:0016579TAS-protein deubiquitination-
GO:0017085IEA-response to insecticide-
GO:0019058TAS-viral life cycle-
GO:0019068TAS-virion assembly-
GO:0019083TAS-viral transcription-
GO:0019985TAS-translesion synthesis-
GO:0030512TAS-negative regulation of transforming growth factor beta receptor signaling pathway-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0032479TAS-regulation of type I interferon production-
GO:0032480TAS-negative regulation of type I interferon production-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0033683TAS-nucleotide-excision repair, DNA incision-
GO:0034220TAS-ion transmembrane transport-
GO:0035635TAS-entry of bacterium into host cell-
GO:0035666TAS-TRIF-dependent toll-like receptor signaling pathway-
GO:0036297TAS-interstrand cross-link repair-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0038128TAS-ERBB2 signaling pathway-
GO:0042059TAS-negative regulation of epidermal growth factor receptor signaling pathway-
GO:0042276TAS-error-prone translesion synthesis-
GO:0042769TAS-DNA damage response, detection of DNA damage-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043066TAS-negative regulation of apoptotic process-
GO:0043123TAS-positive regulation of I-kappaB kinase/NF-kappaB signaling-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043488TAS-regulation of mRNA stability-
GO:0044267TAS-cellular protein metabolic process-
GO:0045087TAS-innate immune response-
GO:0045742TAS-positive regulation of epidermal growth factor receptor signaling pathway-
GO:0045944TAS-positive regulation of transcription from RNA polymerase II promoter-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051092TAS-positive regulation of NF-kappaB transcription factor activity-
GO:0051403TAS-stress-activated MAPK cascade-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0060544TAS-regulation of necroptotic process-
GO:0061024TAS-membrane organization-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0070423TAS-nucleotide-binding oligomerization domain containing signaling pathway-
GO:0070911TAS-global genome nucleotide-excision repair-
GO:0070987TAS-error-free translesion synthesis-
GO:0075733TAS-intracellular transport of virus-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
GO:1901796TAS-regulation of signal transduction by p53 class mediator-
GO:1904380TAS-endoplasmic reticulum mannose trimming-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBA52CD3D11315917872946 Affinity Capture-Western
UBA52CD3D10735317872946 Affinity Capture-Western
UBA52GRB210914220936779 Two-hybrid
UBA52GRB211315920936779 Two-hybrid
UBA52SMAD111315911438941 Two-hybrid
UBA52SMAD111026111438941 Two-hybrid
UBA52UBA521131598107144 Co-crystal Structure
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98887
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051023-7'