Annotation Details for UBA7

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	UBA7 ( D8,MGC12713,UBA1B,UBE1L,UBE2 )
Gene Full Name:	ubiquitin-like modifier activating enzyme 7
Band:	3p21.31
Quick Links	Entrez ID:7318; OMIM: 191325; Uniprot ID:UBA7_HUMAN; ENSEMBL ID: ENSG00000182179; HGNC ID: 12471
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:2 results
Molecular Function:4 results
Biological Process:6 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005654	TAS	-	nucleoplasm	-
GO:0005829	TAS	-	cytosol	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004842	EXP	-	ubiquitin-protein transferase activity	18583345
GO:0005515	IPI	-	protein binding	16189514
GO:0005524	IEA	-	ATP binding	-
GO:0019782	IDA	-	ISG15 activating enzyme activity	16428300

GO ID	Evidence	Qualifier	GO_term	References
GO:0006464	IDA	-	cellular protein modification process	16428300
GO:0016567	IEA	-	protein ubiquitination	-
GO:0019941	IEA	-	modification-dependent protein catabolic process	-
GO:0019985	TAS	-	translesion synthesis	-
GO:0032020	IDA	-	ISG15-protein conjugation	16428300
GO:0032480	TAS	-	negative regulation of type I interferon production	-

Protein-Protein Interaction

BioGRID:2 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
ISG15	UBA7	114995	16189514 16884686	Affinity Capture-MS; Two-hybrid
ISG15	UBA7	113166	16189514 16884686	Affinity Capture-MS; Two-hybrid

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1349462
Data Attributes: HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved